Sex-specific dispersal and evolutionary rescue in metapopulations infected by male killing endosymbionts
© Bonte et al; licensee BioMed Central Ltd. 2009
Received: 15 July 2008
Accepted: 16 January 2009
Published: 16 January 2009
Male killing endosymbionts manipulate their arthropod host reproduction by only allowing female embryos to develop into infected females and killing all male offspring. Because the resulting change in sex ratio is expected to affect the evolution of sex-specific dispersal, we investigated under which environmental conditions strong sex-biased dispersal would emerge, and how this would affect host and endosymbiont metapopulation persistence.
We simulated host-endosymbiont metapopulation dynamics in an individual-based model, in which dispersal rates are allowed to evolve independently for the two sexes. Prominent male-biased dispersal emerges under conditions of low environmental stochasticity and high dispersal mortality. By applying a reshuffling algorithm, we show that kin-competition is a major driver of this evolutionary pattern because of the high within-population relatedness of males compared to those of females. Moreover, the evolution of sex-specific dispersal rescues metapopulations from extinction by (i) reducing endosymbiont fixation rates and (ii) by enhancing the extinction of endosymbionts within metapopulations that are characterized by low environmental stochasticity.
Male killing endosymbionts induce the evolution of sex-specific dispersal, with prominent male-biased dispersal under conditions of low environmental stochasticity and high dispersal mortality. This male-biased dispersal emerges from stronger kin-competition in males compared to females and induces an evolutionary rescue mechanism.
Parasites can induce host population extinction through negative effects on population growth . This effect can be amplified by the induction of host behaviour that stimulates parasite spreading [1–3]. Some bacterial endosymbionts that that are predominantly vertically transmitted from females to their offspring can be regarded as such parasites. They are widespread in arthropods and manipulate reproduction of their host [4, 5]. The induced reproductive manipulations comprise parthenogenesis (i.e. infected virgin females produce daughters), feminization (infected genetic males reproduce as females), cytoplasmatic incompatibility (CI; in its simplest form the mating between infected males and uninfected females leads to the death of embryos), and male killing (i.e. infected male embryos die while infected female embryos develop into infected females). Male-killing imposes substantial costs at the individual level (both on infected females and on the males that mate with them) since the death of male offspring halves the number of viable offspring. Such male-killing endosymbionts are known from butterflies, ladybird beetles and flies, in which they affect sex ratio and related life-history parameters . If both, endosymbiont transmission and host manipulation occur with near-perfect efficiency, infections can approach (near) fixation and host extinction will occur when all males are eliminated out of the population [6, 7]. However, Randerson and colleagues  showed that hosts can avoid extinction by adaptive alterations of sexual behaviour, thereby raising their inclusive fitness. A prominent example comprises male-killing bacteria that trigger increasing male fatigue and female promiscuity in infected population of a butterfly .
Male killing endosymbionts clearly impair individual fitness of infected males (and implicitly of the males mating with them). Yet, the invasion of male-killers in a metapopulation has strong and more complex effects on the population structure. First, effective population sizes are strongly reduced due to skewed sex ratios . This is expected to lead to a reduction in genetic variation , which subsequently reduces the effectiveness of selection against deleterious mutations  and the rate of adaptive evolution [13, 14]. Secondly, endosymbionts reduce population density and thus relax intraspecific competition . This relaxation is mainly among kin when eggs are laid in clutches and female offspring benefit from the death of their brothers by e.g. lowered resource competition in a later life phase [15, 16]. Alternatively, male death enhances the fitness of their infected female siblings by prevention of inbreeding . However, when competition takes place among all patch inhabitants male-killing endosymbionts reduce competition among offspring, thereby potentially benefiting surviving individuals within the local population indifferently of their infection status. This can lead, under certain conditions, to the spread of male-killing endosymbionts in metapopulations (by beneficial group trait selection) in absence of any explicit fitness compensation .
At any rate, male-killing endosymbionts have the ability to alter the demographic properties of their host population by inducing female-biased sex ratios. In combination with environmental factors related to dispersal mortality and demographic stochasticity these changes in population structure are expected to have a strong influence on the evolution of dispersal in spatially structured populations [19–25]. In a previous contribution , we already showed that the invasion of male killers selects for increased dispersal under conditions of low environmental stochasticity and high dispersal mortality. These evolved dispersal rates subsequently provoked extinction-colonization dynamics among patches in the metapopulation, thereby leading to stable infection frequencies (from here-on referred to as infection rates), metapopulation extinction of host and endosymbiont, or endosymbiont extinction only. Yet, because male-killing endosymbionts induce pronounced sex-specific effects on fitness and kin structure, they should also influence the evolution of dispersal differently in males and females. This is in agreement with the general predictions of Leturque & Rousset  that evolved changes in sex ratio may lead to higher dispersal rates and trigger the evolution of sex-specific dispersal. A theoretical background for the evolution of sex-biased dispersal is, however, poorly developed. Perrin & Mazalov  showed that mating systems are expected to be an important driver of sex-biased dispersal because sex-specific differences in potential reproductive success affect the balance between local resource mate competition and local resource competition.
When populations occupy spatially structured habitat, evolutionary changes in dispersal may rescue populations from (human induced) changes in habitat availability and quality . These adaptive responses can indeed occur in fairly short time spans, as, for example, shown for wind dispersing arthropods [29, 30] and vascular plants . Metapopulation curing, i.e. the deterministic extinction of parasites but not the host, under environmental conditions that select against dispersal  could be another prominent example of such an evolutionary rescue. Because male killing endosymbionts generate strong bias in sex ratio, and increase dispersal rates considerably , we here explore the evolutionary mechanisms leading to male-biased dispersal in infected populations. Secondly, we show that a male-bias in dispersal is responsible for higher rates of metapopulation curing (host extinction) compared to populations with sex-indifferent dispersal.
We build an individual based simulation model that allowed the evolution of sex-specific dispersal strategies in a metapopulation consisting of 100 patches with carrying capacity K, inhabited by sexually reproducing, polygynous organisms. Dispersal is accompanied by costs (μ) that relate to patch isolation. Environmental stochasticity is modelled by a standard deviation (σ) around the number of offspring (λ). Population dynamics follow logistic growth, endosymbionts are maternally transmitted from mother to daughters (male offspring die during the embryonic stage when the mother is infected). Dispersal strategies were determined by two sex-specific dispersal alleles.
Bias in sex-specific dispersal
no infection, no reshuffling
0.55 ± 0.04
no infection, reshuffling
0.55 ± 0.04
infection, no reshuffling
0.61 ± 0.06
0.51 ± 0.04
Strong environmental fluctuations and low dispersal mortality are well-acknowledged factors that support the evolution of high emigration probability [19–25, 32, 33]. Our simulations suggest that the presence of male-killing microbial infections should increase overall dispersal rates, too. When dispersal is assumed to be independent of sex, dispersal probabilities showed a significant increase, particularly for those scenarios otherwise favouring low dispersal (i.e. high dispersal mortality and low environmental stochasticity). However, if allowed for sex-specific dispersal, endosymbionts induced pronounced male-biased dispersal rates. Effects of male-killing endosymbionts on demography and life history in e.g. tropical butterflies , flies  and ladybird beetles  are documented. No attempts have been made, so far, to link infections by male-killing endosymbionts to spatial population structure and dispersal. Our results suggest that this would be a worthwhile endeavour.
The higher rates of patch extinction induced by male-killing endosymbionts compared to metapopulations of uninfected hosts , as well as the benefits of relieved competition in patches that are founded shortly after patch extinction select for higher dispersal rates [24, 37–39]. The relationship between extinction rate and dispersal might, however, become hump-shaped with very high extinction rates selecting for reduced dispersal . Yet in our simulations, as well as in simulations without infection , local extinction rates so high as to select for reduced dispersal never emerged because the system rapidly went globally extinct under such conditions.
Sex-biased dispersal is documented to originate from strategies related to inbreeding avoidance, inbreeding depression, asymmetrical mating systems, social structure, or sex-specific dispersal costs [27, 33, 41]. More generally, the small effective population size and the tighter kin-structure in infected metapopulations due to the rarity of males explain the evolution towards overall higher dispersal rates, compared to metapopulations without male-killing endosymbionts. This particularly holds under conditions of high dispersal mortality and low environmental stochasticity. However, theory generally predicts that strong kin-competition selects against a sex-bias in dispersal , while in our simulations we demonstrate that strong kin-competition is responsible for the emergence of male-biased dispersal. The explanation for this apparent contradiction can be found in the unbalanced cost-benefits for dispersal in males and females. In Gandon's system , males and females played the same game, i.e. they both competed for space and mates and have the same costs of dispersal. Taylor  showed, however, that deviations from these conditions, i.e. sex-specific costs of dispersal and different relatednesses for the two sexes, induce sex-specific dispersal. The latter assumed that a sex bias in relatedness should only be important in haplodiploid populations, but not in diploid organisms. In our system, however, male-killing endosymbionts strongly affect within-population relatedness, because under high infection rates the (few) males in a patch have higher probabilities to share mothers than females. This is due to the fact that in populations with an infection rate I only a fraction of 1-I females produce sons, while all females produce daughters. Like for Taylor's haplodiploid system, the most related sex (females in a haplodiploid system, but males in our case) should thus evolve higher dispersal rates than patchmates from the other sex.
One could also speculate that dispersing males take a greater risk of mating with infected females as the very existence of males in a patch may indicate reduced infection rates in that patch. However, consequences of such an increase in the cost of dispersal could not be observed. Probabilities of mating with uninfected females were not higher for males in their natal patches, because populations may persist at high infection frequencies . Moreover, the particularly strong kin-competition for males overrules this potential (and sporadic) increased chance of finding uninfected females.
Leturque & Rousset  showed that sex-specific dispersal rates may evolve when reproductive values vary among genotypes and when relatedness is high. Interestingly, their model also shows that the incorporation of sex-biased dispersal may lead to a biased sex ratio in offspring production in finite populations and in populations experiencing spatial heterogeneity in habitat quality. In our model, changes in the sex ratio are due to male-killing endosymbionts and lead to higher and sex-biased dispersal. Yet, we could expect that the changes in sex ratio might trigger an evolutionary response also in offspring sex ratio. If a female can recognize its own infection status, infected females should clearly shift the sex ratio in favour of female offspring as the male offspring is killed anyways. Uninfected females should in contrast produce more male offspring as they would have more fitness contribution via sons. However, that only holds for infected populations because in uninfected ones the sex ratio is 1:1. So ideally, such females should response to both, their own infection status and the infection status of the population.
In well connected metapopulations with high inter-patch dispersal, metapopulation extinction probabilities are hardly affected by dispersal. Under these conditions the high dispersal leads to high recolonization rates of empty patches but also to a rapid spread of infections into uninfected populations . Consequently, endosymbiont extinction probabilities are only slightly affected by sex-specific dispersal when dispersal is generally high (even in females). By contrast, deterministic curing of metapopulations increases with sex-specific dispersal strategies. The evolution of sex-specific dispersal leads to considerably lower dispersal probabilities of females (compared to simulations with sex indifferent dispersal) under environmental conditions characterized by high dispersal mortality and low environmental stochasticity. This leads to a comparable decline in recolonization rates of patches by infected females and the spread of infections. The evolution towards male-biased dispersal in infected metapopulations – promoted by the benefit of reduced kin-competition in males – can consequently be regarded as an evolutionary rescue as it increases the probability of curing for the entire metapopulation.
In our simulations we assume global dispersal as opposed to e.g. nearest neighbour dispersal, reflecting airborne dispersal in e.g. arachnids and insects. Because kin-competition is the dominant driver behind the evolution of sex-specific dispersal, we could expect limited dispersal distance (i.e., nearest neighbour dispersal), which maintains some kin-competition even after dispersal, to have a strong influence on the evolutionary dynamics. However, simulation experiments for uninfected metapopulations  as well as our own simulations (Bonte D, Hovestadt T, Poethke HJ, unpub. data) show that the choice of dispersal-mode has little influence on the evolution of ES dispersal probabilities. This is due to intrinsically high dispersal rates and the absence of any spatial autocorrelation in environmental stochasticity. This demonstrates that kin-competition is predominantly generated through changes in local population structure, i.e. the (much) reduced effective population size in infected populations and not by limited dispersal distance.
Kin-competition is documented to select for increased dispersal rates when dispersal cost is high and/or when spatio-temporal variability of environmental conditions is low [21, 25, 42–45]. Male-killing endosymbionts induce strong kin-competition under these environmental conditions, which lead to strong sex-biased dispersal in infected metapopulations. Paradoxically, their induced negative feedbacks on female dispersal rates eventually decrease their own persistence in a host metapopulation. Adaptive dispersal or genotype-biased dispersal strategies are already known to rescue metapopulations from extinction [46–48]. Here we show that evolution of sex-specific dispersal could enhance persistence of hosts that experience infection by male-killing endosymbionts in two different ways: (i) by decreasing host extinction probabilities (minor effect) and (ii) by inducing curing of the host (major effect) through the combined action of increased male and decreased female dispersal. In addition to the finding that adaptive dispersal can promote the evolution of parasite resistance , we here show that an evolutionary response of dispersal strategies to male-killing endosymbiont infection may already as such be an adaptation to escape male-killing endosymbiont infections.
Male killing endosymbionts induce the evolution of sex-specific dispersal, with prominent male-biased dispersal under conditions of low environmental stochasticity and high dispersal mortality. This male-biased dispersal emerges from kin-competition, which is (much) stronger in males because they are all offspring of the (few) females of their high relatedness. In addition, the evolution of sex-specific dispersal rates induces an evolutionary rescue mechanism by either decreasing endosymbiont fixation probabilities (which subsequently would lead to the crash of the host metapopulation) under conditions of high environmental stochasticity, or increasing endosymbiont extinction (curing) under conditions of low environmental stochasticity.
For our simulation experiments we use an extended version of an individual-based model [23–25] of insect dispersal in patchy landscapes of n (= 100) habitat patches with equal carrying capacities K (= 100).
Each individual is characterized by its sex, its affiliation with a specific patch (i), and by four alleles at two different diploid loci that determine male (d m ), respectively female (d f ) dispersal propensity (see below). At initialization allele values are drawn randomly from a uniform distribution [0–1]. Further, individuals are characterized by their infection status (infected versus uninfected), which they solely inherit from their mother.
Here N i represents the population size in patch i. K is the carrying capacity of each patch in the metapopulation. It is important to recognize that the daughters of an infected mother do not exclusively benefit from the death of their brothers. Yet, in groups with infected females, population growth increases as female offspring are released from competition by males.
In our model, individuals simultaneously disperse before mating and production of offspring; each individual has only one opportunity to disperse. Dispersing individuals die with a probability μ (dispersal mortality), regardless of patch origin. For each individual its emigration probability d is determined by the mean value of their two sex-specific dispersal alleles, (dm,1+dm,2)/2 respectively (df,1+df,2)/2. We assume global dispersal; that is, a successful disperser reaches a patch in the landscape (except its home patch) with the same probability (1-μ)/(n-1). Dispersal probability is thus unconditional, i.e. we assume that dispersal decisions are not based on patch condition (e.g. infection rate, density or sex ratio). However, dispersal alleles were allowed to change by mutation, thus allowing for the evolution of sex-specific dispersal strategies To promote greater variability of genotypes in the first generations and to reduce the influence of mutations on the stability of the final result, we let mutation rates exponentially decrease from ~0.1 to <0.001 over the course of the simulation experiments (5000 generations; see e.g. ). A mutation comprises a change into a new random value from the uniform [0–1] distribution. For the case of symmetric, i.e sex-indifferent dispersal we assume that dispersal is governed by one locus only determining male as well as female dispersal propensity.
To infer how the presence of infections in the metapopulation influenced the evolution of dispersal probability in male and female hosts, we compared results of simulation experiments with and without endosymbiont infection. Experiments with infections were run with sex-specific as well as with symmetric dispersal behaviour. For both sets of experiments we estimated the metapopulation extinction probability (host and endosymbiont go both extinct) and the probability of endosymbiont extinction only ('curing'). Simulations were run with an initial fraction of infected females of I = 0.10 randomly distributed over patches. Additional simulations showed that the initial infection rate did not influence trait evolution (Bonte D, unpublished data). Because (i) we only observed an effect of carrying capacity on metapopulation dynamics and trait evolution when K << 100; and (ii) typical insect habitats can be expected to rarely have capacities below K = 100 , we ran simulations only for values of K = 100.
Simulations were run for different combinations of dispersal mortality (μ = 0.1, 0.15....0.45; 8 values) and environmental stochasticity (σ = 0, 0.5, 1, 1.5 ...4.5; 10 values) resulting in a total of 80 scenarios for each of the simulation experiments described above. All scenarios were replicated 100 times. Global host as well as endosymbiont extinction probability was calculated as the number of simulation runs with metapopulation extinction divided by the total number of replicates for each scenario. Equally, the probability of curing was estimated by dividing the number of cured populations by the number of surviving host populations. In order to test the influence of kin-competition on the observed patterns in dispersal evolution, infection rate, and population dynamics, we applied a reshuffling algorithm by which local kin-structure is destroyed . Here, individuals within each patch i were replaced by individuals of the same sex and with the same infection status randomly selected from the entire pool of individuals in the metapopulation. This experiment was also performed for the 80 scenarios described above with 100 replicates each.
In our simulations, we do not allow for the evolution of host resistance. As shown by Dyer & Jaenike , endosymbionts may have only limited capacity to counter newly evolved host resistance because of their small effective population sizes . Yet the most influential restrictions are probably the applied mating system and the dispersal strategy. Because endosymbionts infections are predominantly associated with arthropods, we assume polygyny since this is the most common mating system in insects and other arthropods ; our simulation results would certainly be very different for a monogamous mating system. Despite evidence that male-killing bacteria may affect sexual selection [9, 55], we only allowed single mating events in order to provide straight mechanisms of inheritance.
DB is a postdoctoral fellow at the Fund for Scientific Research – Flanders (FWO), from which he received a mobility grant for a long-term stay at Würzburg University. HJP and TH are partially supported by a grant from the "Deutsche Forschungsgemeinschaft" (DFG PO233/3). The study was funded by an FWO research grant (G.0057.09).
- Tschirren B, Fitze PS, Richner H: Maternal Modulation of Natal Dispersal in a Passerine Bird: an adaptive strategy to cope with parasitism. Am Nat. 2007, 169: 87-93. 10.1086/509945.View ArticlePubMedGoogle Scholar
- Moore J: Parasites and the behavior of animals. 2002, Oxford, New York, Oxford University PressGoogle Scholar
- Vala F, Egas M, Breeuwer AJ, Sabelis MW: Wolbachia affects oviposition and mating behaviour of its spider mite host. J Evol Ecol. 2004, 17 (3): 692-700.Google Scholar
- Goodacre SL, Martin OY, Thomas CFG, Hewitt GM: Wolbachia and other endosymbiont infections in spiders. Mol Ecol. 2006, 15: 517-527. 10.1111/j.1365-294X.2005.02802.x.View ArticlePubMedGoogle Scholar
- Hurst GDD, Jiggins FM: Male-killing bacteria in insects: mechanisms, incidence, and implications. Emerg Infect Dis. 2000, 6: 329-336.PubMed CentralView ArticlePubMedGoogle Scholar
- Jaenike J, Duer KA, Reed LK: Within-population structure of competition and the dynamics of male-killing Wolbachia. Evol Ecol Res. 2003, 5: 1023-1036.Google Scholar
- Hatcher MJ, Taneyhill DE, Dunn AM, Tofts C: Population dynamics under parasitic sex ratio distortion. Theor Popul Biol. 1999, 56: 11-28. 10.1006/tpbi.1998.1410.View ArticlePubMedGoogle Scholar
- Randerson JP, Jiggins FM, Hurst LD: Male killing can select for male mate choice: a novel solution to the paradox of the lek. Proc Biol Sci. 2000, 267 (1446): 867-874. 10.1098/rspb.2000.1083.PubMed CentralView ArticlePubMedGoogle Scholar
- Charlat S, Reuter M, Dyson EA, Hornett EA, Duplouy A, Davies N, Roderick GK, Wedell N, Hurst GDD: Male-killing bacteria trigger a cycle of increasing male fatigue and female promiscuity. Curr Biol. 2007, 17: 233-277. 10.1016/j.cub.2006.11.068.View ArticleGoogle Scholar
- Engelstadter J, Hurst GDD: The impact of male-killing bacteria on host evolutionary processes. Genetics. 2007, 175: 245-254. 10.1534/genetics.106.060921.PubMed CentralView ArticlePubMedGoogle Scholar
- Kimura M: The Neutral Theory of Molecular Evolution. 1983, Cambrdige, Cambridge University PressView ArticleGoogle Scholar
- Ohta T: Population size and the rate of evolution. J Mol Evol. 1972, 1: 305-314. 10.1007/BF01653959.View ArticleGoogle Scholar
- Fisher RA: The Genetical Theory of Natural Selection. 1930, Oxford, Claredon PressView ArticleGoogle Scholar
- Ohta T: Slightly deleterious mutant substitutions in evolution. Nature. 1973, 246: 96-98. 10.1038/246096a0.View ArticlePubMedGoogle Scholar
- Hurst LD: The incidences and evolution of cytoplasmic male killers. Proc R Soc Lond B. 1991, 244: 91-99. 10.1098/rspb.1991.0056.View ArticleGoogle Scholar
- Hurst GDD, Jiggins FM, Majerus MEN: Inherited microorganisms that kill males. Insect symbiosis. Edited by: Bourtzis K, Miller T. 2003, Florida, CRC Press, 177-197.View ArticleGoogle Scholar
- Werren JH: The coevolution of autosomal and cytoplasmoc sex ratio factors. J Theor Biol. 1987, 124: 317-334. 10.1016/S0022-5193(87)80119-4.View ArticleGoogle Scholar
- Bonte D, Hovestadt T, Poethke H-J: Male-killing endosymbionts: influence of environmental conditions on persistence of host metapopulation. BMC Evol Biol. 8: 243-10.1186/1471-2148-8-243.
- Travis JMJ, Dytham C: Habitat persistence, habitat availability and the evolution of dispersal. Proc R Soc Lond B. 1999, 266: 723-728. 10.1098/rspb.1999.0696.View ArticleGoogle Scholar
- Perrin N, Mazalov V: Local competition, Inbreeding, and the Evolution of Sex-biased dispersal. Am Nat. 2002, 155: 116-127. 10.1086/303296.View ArticleGoogle Scholar
- Gandon S, Michalakis Y: Evolutionarily stable dispersal rate in a metapopulation with extinctions and kin competition. J Theor Biol. 2001, 199: 275-290. 10.1006/jtbi.1999.0960.View ArticleGoogle Scholar
- Metz JA, Gyllenberg M: How should we define fitness in structured metapopulation models? Including an application to the calculation of evolutionarily stable dispersal strategies. Proc R Soc Lond B. 2001, 268: 499-508. 10.1098/rspb.2000.1373.View ArticleGoogle Scholar
- Poethke HJ, Hovestadt T: Evolution of density- and patch-size-dependent dispersal rates. Proc R Soc Lond B. 2002, 269: 637-645. 10.1098/rspb.2001.1936.View ArticleGoogle Scholar
- Poethke HJ, Hovestadt T, Mitesser O: Local extinction and the evolution of dispersal rates: causes and correlations. Am Nat. 2003, 161: 631-640. 10.1086/368224.View ArticlePubMedGoogle Scholar
- Poethke HJ, Pfenning B, Hovestadt T: The relative contributions of individual- and kin-selection in the evolution of density-dependent dispersal rates. Evol Ecol Res. 2007, 9: 41-50.Google Scholar
- Leturque H, Rousset F: Joint evolution of sex ratio and dispersal: conditions for higher dispersal rates from good habitats. Evol Ecol. 2003, 17: 67-84. 10.1023/A:1022405415375.View ArticleGoogle Scholar
- Perrin N, Mazalov V: Dispersal and Inbreeding Avoidance. Am Nat. 1999, 154: 282-292. 10.1086/303236.View ArticlePubMedGoogle Scholar
- Kokko H, López Sepulcre A: From individual dispersal to species ranges: perspectives for a changing world. Science. 2006, 313: 789-790. 10.1126/science.1128566.View ArticlePubMedGoogle Scholar
- Bonte D, Borre Vanden J, Lens L, Maelfait J-P: Geographic variation in wolfspider dispersal behaviour is related to landscape structure. Anim Beh. 2006, 72: 655-662. 10.1016/j.anbehav.2005.11.026.View ArticleGoogle Scholar
- Bonte D, Bossuyt B, Lens L: Aerial dispersal plasticity under different wind velocities in a salt marsh wolf spider. Beh Ecol. 2007, 18: 438-443. 10.1093/beheco/arl103.View ArticleGoogle Scholar
- Cheptou PO, Carrue O, Rouifed S, Cantarel A: Rapid evolution of seed dispersal in an urban environment in the weed Crepis sancta. Proc Natl Acad Sci USA. 2008, 105: 3796-3799. 10.1073/pnas.0708446105.PubMed CentralView ArticlePubMedGoogle Scholar
- Bowler DE, Benton TG: Causes and consequences of animal dispersal stragegies: relating individual behaviour to spatial dynamics. Biol Rev. 2005, 80: 205-225. 10.1017/S1464793104006645.View ArticlePubMedGoogle Scholar
- Ronce O: How does it feel to be like a rolling stone? Ten questions about dispersal evolution. Annu Rev Ecol Evol Syst. 2007, 38: 231-253. 10.1146/annurev.ecolsys.38.091206.095611.View ArticleGoogle Scholar
- Charlat S, Hornett EA, Dyson EA, Ho PPY, Loc NT, Schilthuizen M, Davies N, Roderick GK, Hurst GDD: Prevalence and penetrance variation of male-killing Wolbachia across Indo-Pacific populations of the butterfly Hypolimnas bolina. Mol Ecol. 2005, 14: 3225-3250. 10.1111/j.1365-294X.2005.02678.x.View ArticleGoogle Scholar
- Veneti Z, Toda MJ, Hurst GD: Host resistance does not explain variation in incidence of male-killing bacteria in Drosophila bifasciata. BMC Evol Biol. 2004, 4: 52-10.1186/1471-2148-4-52.PubMed CentralView ArticlePubMedGoogle Scholar
- Majerus TMO, Majerus MEN, Knowles B, Wheeler J, Bertrand D, Kuznetzov VN, Ueno H, Hurst GDD: Extreme variation in the prevalence of inherited male-killing microorganisms between three populations of Harmonia axyridis (Coleoptera: Coccinellidae). Heredity. 1998, 81: 683-691. 10.1046/j.1365-2540.1998.00438.x.View ArticleGoogle Scholar
- Ronce O, Olivieri I: Evolution of reproductive effort in a metapopulation with local extinctions and ecological succession. Am Nat. 1997, 150: 220-249. 10.1086/286064.View ArticlePubMedGoogle Scholar
- Parvinen K, Dieckmann U, Gyllenberg M, Metz JAJ: Evolution of dispersal in metapopulations with local density dependence and demographic stochasticity. J Evol Biol. 2003, 16 (1): 143-153. 10.1046/j.1420-9101.2003.00478.x.View ArticlePubMedGoogle Scholar
- Heino M, Hanski I: Evolution of migration rate in a spatially realistic metapopulation model. Am Nat. 2001, 157: 495-511. 10.1086/319927.View ArticlePubMedGoogle Scholar
- Ronce O, Perret F, Olivieri I: Evolutionary stable dispersal rates do not always increase with local extinction rates. Am Nat. 2001, 155: 485-496. 10.1086/303341.View ArticleGoogle Scholar
- Gandon S: Kin competition, the cost of inbreeding and the evolution of dispersal. J theor Biol. 1999, 200: 345-364. 10.1006/jtbi.1999.0994.View ArticlePubMedGoogle Scholar
- Taylor PD: An inclusive fitness model for dispersal of offspring. J Theor Biol. 1980, 130: 363-378. 10.1016/S0022-5193(88)80035-3.View ArticleGoogle Scholar
- Hamilton WD, May RM: Dispersal in stable habitats. Nature. 1977, 269: 578-581. 10.1038/269578a0.View ArticleGoogle Scholar
- Frank SA: Dispersal polymorphisms in subdivided populations. J Theor Biol. 1986, 122: 303-309. 10.1016/S0022-5193(86)80122-9.View ArticlePubMedGoogle Scholar
- Leturque H, Rousset F: Dispersal, kin competition, and the ideal free distribution in a spatially heterogeneous population. Theor Popul Biol. 2002, 62: 169-180. 10.1006/tpbi.2002.1600.View ArticlePubMedGoogle Scholar
- Hanski I: Metapopulation ecology. 1999, New York, Oxford University Press IncGoogle Scholar
- Hanski I, Saccheri I: Molecular-level variation affects population growth in a butterfly metapopulation. Plos Biology. 2006, 4: e129-10.1371/journal.pbio.0040129.PubMed CentralView ArticlePubMedGoogle Scholar
- Hovestadt T, Poethke HJ: The control of emigration and its consequences for the survival of populations. Ecol Model. 2006, 190: 443-453. 10.1016/j.ecolmodel.2005.03.023.View ArticleGoogle Scholar
- Morgan AD, Gandon S, Buckling A: The effect of migration on local adaptation in a coevolving host-parasite system. Nature. 2005, 437: 253-256. 10.1038/nature03913.View ArticlePubMedGoogle Scholar
- Bellows TS: The descriptive properties of some models for density dependence. J Anim Ecol. 1981, 50: 139-156. 10.2307/4037.View ArticleGoogle Scholar
- Price PW: Insect Ecology. 1997, New York, John Wiley and SonsGoogle Scholar
- Dyer KA, Jaenike J: Evolutionarily Stable Infection by a Male-Killing Endosymbiont in Drosophila innubila. Molecular Evidence From the Host and Parasite Genomes. Genetics. 2004, 168: 1443-1455. 10.1534/genetics.104.027854.PubMed CentralView ArticlePubMedGoogle Scholar
- Moran NA: Accelerated evolution and Muller's rachet in endosymbiotic bacteria. Proc Natl Acad Sci USA. 1996, 93: 2873-2878. 10.1073/pnas.93.7.2873.PubMed CentralView ArticlePubMedGoogle Scholar
- Choe JC, Crespi BJ, (eds): The Evolution of Mating Systems in Insects and Arachnids. 1997, Cambrdige, Cambridge Univ. PressGoogle Scholar
- Charlat S, Hurst GDD, Merçot H: Evolutionary consequences of Wolbachia infections. Trends in Genetics. 2003, 19: 217-223. 10.1016/S0168-9525(03)00024-6.View ArticlePubMedGoogle Scholar
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