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Figure 12 | BMC Evolutionary Biology

Figure 12

From: On the evolutionary conservation of hydrogen bonds made by buried polar amino acids: the hidden joists, braces and trusses of protein architecture

Figure 12

Examples of hydrogen bond interactions from conserved, buried residues to mainchain atoms in coils. Representative structures were chosen for each family based on resolution; residues are coloured by atom type with buried, conserved polar residues shown in magenta. Hydrogen bonds are shown in black. Three examples of polar residues forming hydrogen bonds to coils including, A) a cysteine in the high potential iron-sulphur protein family [PDB: 1isu], two asparates in B) the glycosyl hydrolase family 10 [PDB: 1tax] and C) the serine/threonine protein kinases [PDB: 1hcl].

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