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Table 2 C2 domain similarity compared to corresponding C2 domains from human dysferlin (Type 1) and otoferlin (Type 2).

From: Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins

Type Ferlin C2A C2B C2C C2D C2DE C2E C2F
1 FER1L1_Tadh 37.1 71.4 65 61 72 79 76.9
1 FER1L3_Tadh 47 69.4 62.7 59.1 49.3 80 51.4
1 FER1L1_Nvec   44.5 68.1 55.6   78 76.2
1 FER1L1_Ccap    68.7 60 75 75 80.8
1 FER1L1_Lgig   70.4 68.1 67 52.1 76 76.9
1 FER1L1_Sman   66.3 55.8 59.6   73 79.2
1 FER_Cele    34.6 41.8   66 49.3
1 FER1L1_Bmal    30.6 54.3 49.5 65.3 60.6
2 FER1L2_Tadh   73.3 64.9 66.1   87 72.5
2 FER1L2_Nvec 78.1 72.7 85.7 69.7 53.4 89 78.6
2 FER1L2_Ccap    56.4 64.2   71 78.6
2 FER1L2_Lgig   85.9 89.3 77.1   92 90.1
2 FER1L2_Sman   26.8 57.5 39.3   75 70.2
2 FER1L1_Phum   87.9 87.5 76.1   89 90.8
2 Misfire_Dmel   52.3 37.9 40   66  
  1. Key: The C2DE domain from FER1L2_Nvec was compared to dysferlin C2DE since otoferlin does not contain this corresponding C2 domain. Blank spaces indicate C2 domains not detected by SMART.