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Figure 1 | BMC Evolutionary Biology

Figure 1

From: African signatures of recent positive selection in human FOXI1

Figure 1

Decay of linkage disequilibrium around FOXI1 in Africans. (A). Genes and SNPs in the region. Boxes represent genes and vertical gray lines are SNPs. Underlined SNPs are those constituting core haplotypes. (B). Relative EHH over physical distance. The vertical grey line indicates the core region from which REHH is measured. Red and orange lines show REHH values at increasing distances from the core for the two main extended haplotypes. (C). Breakdown of EHH over genetic distance. The vertical grey line indicates the core region from which EHH is measured. Red and orange lines show EHH values at increasing distances from the core for the two main extended haplotypes (D) Haplotype bifurcation plots for each core haplotype. The dark blue circle in the center of each plot indicates the core and each node represents a SNP (and thus, a possible bifurcation). Blue lines indicate the observed haplotypes and the thickness of the branch is proportional to the haplotype frequency in the population.

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