BMC Ecology and Evolution

Table 1 Amino acid similarity between tetrapod and teleost EGF receptor subdomains

From: Lineage-specific co-evolution of the Egf receptor/ligand signaling system

Extra-cellular domain
	Hsa	Mmu	Gga	Ola	Xma	Dre	Tni	Tru	Gac
Hsa	100
Mmu	88	100
Gga	72	72	100
Ola	57	56	57	100
Xma	55	54	56	80	100
Dre	58	56	58	66	63	100
Tni	55	57	57	75	74	64	100
Tru	55	55	57	79	76	66	86	100
Gac	55	55	57	80	75	65	75	79	100
Trans- and Juxta-membrane
	Hsa	Mmu	Gga	Ola	Xma	Dre	Tni	Tru	Gac
Hsa	100
Mmu	91	100
Gga	85	88	100
Ola	74	72	77	100
Xma	74	72	75	90	100
Dre	80	81	82	81	82	100
Tni	75	74	78	91	94	85	100
Tru	75	74	78	90	94	87	97	100
Gac	75	74	78	90	91	84	95	94	100
Tyrosine kinase domain
	Hsa	Mmu	Gga	Ola	Xma	Dre	Tni	Tru	Gac
Hsa	100
Mmu	98	100
Gga	97	97	100
Ola	90	90	91	100
Xma	90	90	91	96	100
Dre	89	89	91	95	94	100
Tni	88	88	88	91	93	93	100
Tru	91	91	92	96	97	95	95	100
Gac	91	91	92	94	95	95	94	97	100

Similarity percentages between human (Hsa), mouse (Mmu), chicken (Gga), medaka (Ola), platyfish (Xma), zebrafish (Dre), green-spotted pufferfish (Tni), fugu (Tru) and three-spined stickleback (Gac) Egfr extracellular, trans- and juxta-membrane and intracellular tyrosine kinase domains.

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ISSN: 2730-7182

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