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Table 3 Enrichment of neuropsychiatric diseases lists by LRGs

From: Schizophrenia and vitamin D related genes could have been subject to latitude-driven adaptation

Disease

Overlap with LRGs

Total count

P-value*

Adjusted p-value§

Schizophrenia

85

885

4 × 10-6

1.6 × 10-5

Parkinson's disease

40

490

0.021

0.084

Multiple sclerosis

16

178

0.058

0.232

Alzheimer's disease

45

618

0.075

0.3

  1. For each disease genes list, it is reported the number of LRGs present, the total size of the list and the significance of the overlap.
  2. * Fisher's exact test; § Bonferroni adjusted p-value