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Table 1 The GenoPheno correlation for similar ethnic groups at similar regions

From: A worldwide correlation of lactase persistence phenotype and genotypes

Population Lactase persistence genotype data Lactase persistence phenotype data Genotype-phenotype correlation
Continent Country Population N Sum of LP-associated alleles frequency Predicted LP freq. Ref. N Pheno. Freq. Testing method Ref. GenoPheno P-value Genotype - phenotype quantitative difference
Africa Nigeria Yoruba 50 0.00 0.00 [18] 48 0.17 BG [43] 0.5670 0.17
Africa Senegal Wolof 118 0.00 0.00 [24] 53 0.51 BG [44] <0.00005 0.51
Africa Sudan Beni Amer 162 0.26 0.45 [24] 40 0.88 BH [45] <0.00005 0.42
Africa Uganda Bantu 44 0.00 0.00 [8] 17 0.06 BG [46] 0.7552 0.06
Asia China Kazakh 94 0.00 0.00 [47] 195 0.24 BH [48] 0.0026 0.24
Asia India Indian 68 0.07 0.14 [7] 38 0.00 BIOPSY [49] 0.0024 -0.14
Asia Japan Japanese 62 0.00 0.00 [18] 40 0.28 BG [50] 0.0432 0.28
Asia North India Northern Indian 128 0.33 0.55 [7] 136 0.55 BG [51, 52] 1.0000 0.00
Asia Russia Komi 20 0.15 0.28 [23] 56 0.38 BG [53] 0.9248 0.10
Europe Finland Finns 1876 0.58 0.82 [23] 638 0.83 BIOPSY [54] 0.3686 0.01
Europe Greece Greek 100 0.09 0.17 [40] 200 0.25 BH [55] 0.8136 0.08
Europe Hungary Hungarian 110 0.62 0.86 [56] 262 0.59 BH [57] <0.00005 -0.26
Europe Ireland Irish 65 0.95 1.00 [8] 50 0.96 BG [58] 0.6014 -0.04
Europe Italy Sardinian 153 0.07 0.14 [40] 47 0.15 BH [59] 0.5530 0.01
Europe Italy North Italian 28 0.36 0.59 [18] 208 0.49 BH [60] 0.3348 -0.10
Europe Italy Central Italian 98 0.11 0.21 [40] 65 0.82 BG [61] <0.00005 0.61
Europe Italy Southern Italian 189 0.08 0.15 [40] 99 0.46 BH [62] <0.00005 0.31
Near/Middle East Afghanistan Tadjik 98 0.30 0.51 [7] 79 0.18 BG [63] <0.00005 -0.33
Near/Middle East Afghanistan Pashtu 16 0.10 0.19 [18] 71 0.21 BG [63] 0.3588 0.02
Near/Middle East Iran Iranian 42 0.10 0.19 [23] 21 0.14 BG [64] 0.4154 -0.05
Near/Middle East Israel Arabs 160 0.05 0.10 [24] 67 0.19 BG [65] 0.8966 0.10
Near/Middle East Jordan Jordanian 112 0.11 0.20 [23] 162 0.76 BH [66] <0.00005 0.55
Near/Middle East Pakistan Balochi 50 0.00 0.00 [18] 32 0.38 BH [67] 0.0036 0.38
Near/Middle East Saudi Arabia Bedouin 94 0.48 0.73 [23] 21 0.81 BH [68] 0.5166 0.08
Near/Middle East Turkey Turks 98 0.03 0.06 [8] 126 0.30 BH [69] 0.0076 0.24
  1. GenoPheno was used to calculate the P-value for lack of correlation between the predicted phenotype (based on all 4 known LP-associated alleles) and the observed phenotype at locations where the ethnic groups were similar, and so expected to have a good genotype-phenotype correlation. Unlike figures 5 and 6, interpolation was not used here, but rather observed points analyses.