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Table 1 Characteristics of adaptive substitutions in the D promoter of ϕX174 that arose in previous evolution experiments.

From: Positive selection at high temperature reduces gene transcription in the bacteriophage ϕX174

Strain Mutation Change in Protein C # of Exps Host* Temperature, °C*
mut319 G 319 T V63F 4** Salmonella typhimurium 43.5
    2, 1 Escherichia coli 37, 43.5
mut321 T 321 C none 1 Salmonella typhimurium 43.5
mut323 A 323 G N64G 3 Salmonella typhimurium 43.5
    1 Escherichia coli 43.5
mut324 C 324 T none 1 Shigella sonnei 42
    1 Escherichia coli 43.5
  1. *Conditions under which substitutions arose [HA Wichman, pers. comm.; [3538]]
  2. ** Also, one reversion after switch to E. coli host at 43.5°C.