Figure 2

Type-2 A isoform-specific region. The type-2 A isoform-specific region contained four conserved microdomains and two conserved N-terminal sequences (DLKHE and ΨAYRG). (A) Schematic representation of the type-2 A isoform-specific regions. Positions of the two N-terminal sequences, the SUMOylation motif, the NLS, the (D/E)(D/E) residues, and the A-box are indicated by colored boxes. (B) The alignment and Sequence Logo representation of the N-terminal region and the conserved microdomains of the type-2 A isoform-specific region. The amino acid residues are represented in the default color scheme of ClustalX. Asterisks indicate identical residues and colons indicate similar residues.