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Figure 7 | BMC Evolutionary Biology

Figure 7

From: Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes

Figure 7

Profile logos of ATP-binding and ATP-hydrolysis sites in chaperonin proteins. Sequence profiles of ATP/ADP-binding and ATP-hydrolysis sites for CCTs, CCT8L and BBS (MMKS, BBS10 and BBS12) proteins from the multiple sequence alignments of sequences obtained from the species listed in the legend for Figure 2. Letters indicate the amino acid types observed at each position. The height of each stack of symbols in each position is proportional to the information content at that position and the height of each letter within the stack is proportional to the frequency of the corresponding residue at that position. Residues involved in direct contacts with base, ribose or phosphate groups, as determined by homology to the known thermosome structures, are indicated.

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