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Table 1 Parameters used in the model

From: The evolution of plasmid-carried antibiotic resistance

Parameter Description
n F Density of wild-type/plasmid-free cells ('F' in figures)
n C Density of cells with resistance on the chromosome ('C' in figures)
n P Density of cells infected with a resistance-carrying plasmid ('Plasmids' in figures)
n B Density of cells infected with a non-coding plasmid ('B' in figures)
n CP Density of cells with resistance both on the chromosome and on a plasmid ('CP' in figures)
n CB Density of cells infected with a non-coding plasmid, and with resistance on the chromosome ('CB' in figures)
N Total density of cells N = n F +n C +n P +n B +n CP +n CB
A Concentration of antibiotic
l Rate of decay of antibiotic
θ Treatment dosage of antibiotic
τ Interval between antibiotic treatments
r Intrinsic per-capita growth rate of cells
a Extrinsic density-dependent death rate of cells
m Death rate of non-resistant cells, due to antibiotic
c C Cost of antibiotic resistance when gene carried on chromosome
c P Cost of antibiotic resistance when gene carried on plasmid
x Cost of plasmid carriage
β Rate of horizontal transfer of plasmids
s Rate of segregation