From: The mode and tempo of hepatitis C virus evolution within and among hosts
Data set | Molecular clock model | Coalescent Modela | Marginal Log Likelihood | Genomic rate of evolutionb(×10-3subs./site/year) | Relaxed clock coefficient of variation | Relative rate of evolution (codon positions 1 & 2) | Relative rate of evolution (codon position 3) |
---|---|---|---|---|---|---|---|
Among-host (1a) | Strict | Constant | -90901.35 | 1.30 (1.16 - 1.43) | Not applicable | 0.72 (0.70 - 0.74) | 1.56 (1.51 - 1.60) |
 | Relaxed | Constant | -90632.03 | 1.44 (1.00 - 1.84) | 0.25 (0.21 - 0.30) | 0.72 (0.70 - 0.74) | 1.56 (1.51 - 1.60) |
 | Relaxed | Expo | -90632.39 | 1.47 (1.02 - 1.87) | 0.24 (0.20 - 0.29) | 0.72 (0.70 - 0.74) | 1.56 (1.51 - 1.60) |
 | Relaxed | BSP | -90632.49 | 1.48 (1.09 - 1.84) | 0.23 (0.20 - 0.27) | 0.72 (0.70 - 0.75) | 1.55 (1.51 - 1.60) |
Among-host (1b) | Strict | Constant | -88288.70 | 1.04 (0.87 - 1.22) | Not applicable | 0.66 (0.64 - 0.68) | 1.68 (1.63 - 1.72) |
 | Relaxed | Constant | -88127.66 | 1.25 (0.73 - 1.73) | 0.22 (0.18 - 0.26) | 0.66 (0.64 - 0.68) | 1.68 (1.64 - 1.72) |
 | Relaxed | Expo | -88125.80 | 1.24 (0.75 - 1.74) | 0.21 (0.17 - 0.25) | 0.66 (0.64 - 0.68) | 1.68 (1.64 - 1.72) |
 | Relaxed | BSP | -88127.55 | 1.18 (0.67 - 1.65) | 0.21 (0.17 - 0.25) | 0.66 (0.64 - 0.68) | 1.68 (1.63 - 1.72) |
Within-host | Strict | Constant | -31070.20 | 1.12 (1.02 - 1.23) | Not applicable | 0.58 (0.54 - 0.61) | 1.85 (1.78 - 1.92) |
 | Relaxed | Constant | -31013.86 | 1.11 (0.97 - 1.23) | 0.27 (0.19 - 0.37) | 0.58 (0.54 - 0.61) | 1.85 (1.78 - 1.92) |
 | Relaxed | Expo | -31013.56 | 1.13 (1.01 - 1.27) | 0.30 (0.19 - 0.42) | 0.58 (0.54 - 0.61) | 1.85 (1.78 - 1.92) |
 | Relaxed | BSP | -31012.14 | 1.11 (0.98 - 1.24) | 0.27 (0.19 - 0.34) | 0.58 (0.54 - 0.61) | 1.85 (1.78 - 1.92) |