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Table 3 MLHKA tests

From: Balancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolving

Region

Pop.a

MLHKA

 
  

kb

p

TAP2

CEU

3.69

1.1 × 10-3

 

YRI

4.94

6.4 × 10-5

 

EAS

5.11

3.2 × 10-5

CDSN/PSORS1C1

CEU

4.79

1.6 × 10-4

 

YRI

3.88

1.6 × 10-5

 

EAS

5.66

1.6 × 10-7

TRIM10/TRIM40

CEU

3.82

5.5 × 10-4

 

YRI

2.23

2.1 × 10-2

 

EAS

4.21

3.9 × 10-5

BTNL2

CEU

5.57

6.4 × 10-7

 

YRI

5.44

1.7 × 10-6

 

EAS

10.80

5.6 × 10-13

  1. a population
  2. bselection parameter (k>1 indicates an excess of polymorphism relative to divergence)