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Table 1 Nucleotide diversity in the different functional classes

From: Genetic adaptation of the antibacterial human innate immunity network

Category

N

Ï€ AFRa

(× 10 -4)

Ï€ AFR

CDSb

(× 10 -4)

Ï€ EURa

(× 10 -4)

Ï€ EUR

CDSb

(× 10 -4)

Receptors

19

9.3

7.1

6.1

4.8

Adaptors

10

5.7

3.0

4.8

3.2

Modulators

6

7.9

3.2

6.3

3.4

Cytokines

69

8.8

5.8

7.2

4.7

Acute Phase

20

9.8

6.8

8.6

5.9

Cellular Immunity

10

8.6

4.4

7.0

3.3

Antiinflammatory Cytokines

10

8.1

4.1

6.3

4.2

Neutrophil

9

7.5

4.4

6.2

4.3

Chemokines

14

8.1

6.6

6.4

4.9

Extracellular

6

10.0

7.5

7.6

3.7

Effector

23

9.2

6.1

7.1

4.0

TOTAL

127

8.6

5.6

6.7

4.3

  1. a Whole sequence. b Coding sequence.
  2. π, nucleotide diversity (average of pairwise differences).
  3. N, number of genes included in each category.