Figure 4

Structural alignment of aSelBL and EF-Tu-Cys-tRNACys. aSelBL ("EF-Pyl", PDB ID 2ELF) is shown in bronze and EF-Tu-Cys-tRNACys (PDB 1B23) is shown in pale blue and green, for EF-Tu and tRNA respectively. The inset box shows a more detailed view of the aminoacyl-binding pocket. Residues lining the pocket are shown in red for aSelBL, with equivalent EF-Tu sites in blue. Residue labels use M. mazei numbering, with Figure 2 alignment numbers in parentheses.