Maximum likelihood tree of CoA-substrate related carboxyl tranferase (CCT) domain sequences. This tree is based on 179 representative sequences and 438 conserved sites and was midpoint rooted. Numbers at nodes indicate bootstrap robustness values higher than 50. Triangles correspond to collapsed groups of eukaryotes. Colors on leaves represent the affiliation of the sequences to their respective domain of life: archaea (red), bacteria (blue) and eukaryotes (green). Bars on the right report the functional assignment of the sequences; sequences that are not in front of any bar are assumed to bear an acyl-CoA carboxylase activity.