Computational archaeology of the Pristionchus pacificus genome reveals evidence of horizontal gene transfers from insects

Table 2 Pfam domains in HGT candidates

Accession ID	Description	N	Enrichment	p-value
PF00078.20	Reverse transcriptase (RNA-dependent DNA polymerase)	58	14.0×	<10^-49
PF03372.16	Endonuclease/Exonuclease/phosphatase family	27	18.8×	<10^-26
PF00096.19	Zinc finger, C2H2 type	14	5.1×	<10^-5
PF00067.15	Cytochrome P450	11	2.5×	<0.01
PF00069.18	Protein kinase domain	9	0.9×	1
PF07714.10	Protein tyrosine kinase	9	1.0×	0.9
PF00097.18	Zinc finger, C3HC4 type (RING finger)	8	3.1×	<0.01
PF00089.19	Trypsin	6	6.4×	<0.01
PF08036.4	Diapausin family of antimicrobial peptide	6	38.3×	<10^-8
PF08953.4	Domain of unknown function (DUF1899)	6	25.6×	<10^-6
PF00076.15	RNA recognition motif (RRM)	5	1.6×	0.3
PF00644.13	Poly(ADP-ribose) polymerase catalytic domain	5	24.0×	<10^-5
PF00856.21	SET domain	5	5.8×	<0.01
PF03732.10	Retrotransposon gag protein	5	24.0×	<10^-5
PF12171.1	Zinc-finger double-stranded RNA-binding	5	3.8×	<0.05
PF00092.21	von Willebrand factor type A domain	4	3.2×	0.06
PF00106.18	short chain dehydrogenase	4	1.4×	0.4
PF00178.15	Ets-domain	4	8.5×	<0.01
PF00005.20	ABC transporter	3	1.4×	0.6
PF00098.16	Zinc knuckle	3	3.7×	<0.05

The 20 most abundant Pfam domains (e-value <0.001) in 509 HGT candidates defined by cross-species homology are shown. Enrichments factors and FDR corrected p-values were calculated relative to all P. pacificus genes with annotated PFAM domains.

ISSN: 2730-7182