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Table 2 Diversity Indices and Neutrality tests for geographical region Beringia, North America, Central America and South America based on mtDNA coding region (np 577 - 16023) sequences.

From: Large scale mitochondrial sequencing in Mexican Americans suggests a reappraisal of Native American origins

Population/Geographic Region

n b

Nucleotide Diversity (SD)%c

θ k (95% CI)

θ s (SD)

θ π (SD)

Tejima's D

P- value d

Fu's Fs

P- value d

Diversity in geographic regions

      

Beringia

66 e

0.0959 (0.0482)

14.198 (8.4 - 23.4)

11.136 (3.241)

14.811 (7.441)

1.021

0.892

0.448

0.645

North America f

73

0.1747 (0.0858)

1338.057 (469.4 - 4380.0)

56.465 (14.649)

27.006 (13.258)

-2.042

0.004

-24.041

0.000

Central America f

139a

0.1735 (0.0846)

917.489 (532.7 - 1664.5)

70.373 (16.098)

26.820 (13.079)

-2.195

0.000

-23.787

0.004

South America f

75

0.1834 (0.0899)

413.514 (203.6 - 908.3)

52.168 (13.563)

28.326 (13.890)

-1.847

0.011

-24.048

0.001

Within haplogroup diversity in respective geographic regions

    

HaplogroupA2

    

North America

29

0.0615 (0.0323)

415.445 (108.5 - 1745.1)

24.485 (7.837)

9.494 (4.986)

-2.569

0.000

-21.684

0.000

Central America

86

0.0495 (0.0258)

465.938 (239.7 - 972.2)

40.591 (10.376)

7.651 (3.991)

-2.816

0.000

-24.854

0.000

South America

17

0.0602 (0.0326)

141.445 (36.0 - 601.3)

21.001 (7.691)

9.294 (5.029)

-2.376

0.001

-9.819

0.001

Haplogroup B2

        

North America

18

0.0668 (0.0358)

158.779 (40.6 - 673.9)

20.351 (7.364)

10.320 (5.525)

-2.471

0.000

-10.079

0.001

Central America

55

0.0539 (0.0281)

261.236 (120.8 - 614.9)

28.850 (8.115)

8.330 (4.346)

-2.598

0.000

-24.826

0.000

B2 South America

22

0.0586 (0.0313)

216.779 (55.9 - 916.5)

18.928 (6.565)

9.048 (4.832)

-2.415

0.000

-12.381

0.000

Haplogroup C1

        

North America

14

0.0487 (0.0271)

82.112 (20.6 - 352.2)

13.836 (5.432)

7.516 (4.193)

-1.994

0.009

-5.519

0.005

Central America

61

0.0501 (0.0262)

221.898 (112.1 - 468.9)

27.351 (7.564)

7.741 (4.054)

-2.510

0.000

-24.908

0.000

South America

17

0.0527 (0.0288)

57.228 (18.5 - 196.2)

14.790 (5.520)

8.147 (4.451)

-1.908

0.017

-5.787

0.012

Haplogroup D1

        

North America

12

0.0363 (0.0211)

69.779 (17.4 - 300.2)

10.596 (4.402)

5.606 (3.259)

-2.125

0.001

-7.565

0.000

Central America

17

0.0425 (0.0237)

141.445 (36.0 - 601.3)

12.719 (4.796)

6.574 (3.657)

-2.235

0.002

-12.457

0.000

South America

19

0.0491 (0.0268)

45.013 (16.5 - 133.6)

12.017 (4.436)

7.591 (4.141)

-1.488

0.047

-6.217

0.004

  1. a Randomly selected from total 219 sequences to overcome computational limitation.
  2. b Sample size.
  3. c Nucleotide diversity (standard deviation) multiplied with 100.
  4. d Significant P-values < 0.05 (for Tajima's D) and < 0.02 (for Fu's Fs).
  5. e Samples belonging to sub haplogroups (A2a, A2b and D2) in Chukchi, Eskimos, and Aleuts populations from Siberia and Commander Island.
  6. f Samples belonging to pan American haplogroups (A2, B2, C1 and D1) only
  7. SD: Standard deviation