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Table 2 Comparison of sequence substitution rates of RHOXF1 and RHOXF2 in primates

From: Rapid evolution and copy number variation of primate RHOXF2, an X-linked homeobox gene involved in male reproduction and possibly brain function

  Human lineage Non-human primates lineage
  lineage N/S Ka/Ks lineage N/S Ka/Ks
  A-HUM 5/1 1.01 A-CHP 11/0
  B-HUM 9/1 1.99 B-GOR 6/4 0.72
RHOXF2 C-HUM 22/3 2.60* C-ORA 9/7 0.61
  D-HUM 27/5 2.18 D-SIA 19/6 1.59
  E-HUM 33/7 1.24 E-RM 22/11 0.96
  A-HUM 0/3 0 A-CHP 5/1 1.52
RHOXF1 B-HUM 1/3 0.10 B-GOR 5/3 0.50
  C-HUM 6/4 0.44 C-ORA 4/3 0.38
  E-HUM 14/5 0.83 E-RM 13/1 3.87
  1. Note: A-E are the inferred ancestral nodes of the primate phylogenetic tree (figure 2). N/S indicates the number of non-synonymous substitutions and the number of synonymous substitutions of each lineage. *Ka/Ks > 1, P = 0.026 (Z test)