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Table 2 Comparison of sequence substitution rates of RHOXF1 and RHOXF2 in primates

From: Rapid evolution and copy number variation of primate RHOXF2, an X-linked homeobox gene involved in male reproduction and possibly brain function

 

Human lineage

Non-human primates lineage

 

lineage

N/S

Ka/Ks

lineage

N/S

Ka/Ks

 

A-HUM

5/1

1.01

A-CHP

11/0

∞

 

B-HUM

9/1

1.99

B-GOR

6/4

0.72

RHOXF2

C-HUM

22/3

2.60*

C-ORA

9/7

0.61

 

D-HUM

27/5

2.18

D-SIA

19/6

1.59

 

E-HUM

33/7

1.24

E-RM

22/11

0.96

 

A-HUM

0/3

0

A-CHP

5/1

1.52

RHOXF1

B-HUM

1/3

0.10

B-GOR

5/3

0.50

 

C-HUM

6/4

0.44

C-ORA

4/3

0.38

 

E-HUM

14/5

0.83

E-RM

13/1

3.87

  1. Note: A-E are the inferred ancestral nodes of the primate phylogenetic tree (figure 2). N/S indicates the number of non-synonymous substitutions and the number of synonymous substitutions of each lineage. *Ka/Ks > 1, P = 0.026 (Z test)