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Table 3 Divergence times of major splits in the malarial phylogeny as estimated by MultiDivTime and BEAST

From: Timing the origin of human malarias: the lemur puzzle

Calibrations: node56, min = 6, max = 8; ABSMAX = 91

Ā 

MultiDivTime (MDT)

Beast

Ā 

Divergence

Node

Node Age (Mya)

95% CrI

Node Age (Mya)

95% CrI

cCrIs

Origin of Southerm Asia Macaca species

55

4.55

3.53, 5.64

3.62

2.76, 4.60

2.76-5.64

Split P. cynomolgi-P. vivax

52

2.50

1.77, 3.39

2.09

1.31, 2.90

1.31- 3.39

Origin of Catarrhini parasite (excluding P. ovale)

57

14.20

11.22, 17.48

13.52

10.26, 17.29

10.26-17.48

Split Papio-Macaca

56

7.39

6.26, 7.98

6.79

6.00, 7.80

6.00-7.98

Lorisiforms-Catarrhini parasite

58

16.31

12.75, 20.38

15.66

12.14, 19.67

12.14-20.38

Radiation Lorisiforms parasite

42

12.31

9.19, 16.05

12.41

9.52, 15.78

9.19-16.05

Radiation Apes parasite

35

9.07

6.12, 12.9

9.80

6.97, 13.06

6.12-13.06

Radiation Rodents parasite

38

9.57

6.62, 13.36

7.61

5.30, 10.34

5.30-13.36

Split P. falciparum-P. reichenowi

33

2.96

1.75, 4.71

3.42

2.25, 4.67

1.75-4.71

Origin of P. falciparum

31

0.27

0.03, 0.67

0.25

0.10, 0.43

0.03-0.67

Origin of Plasmodium in mammals

60

24.97

19.04, 32.27

21.56

16.46, 26.86

16.46-32.27

Calibrations: node56, min = 6, max = 14.3; ABSMAX = 91

Ā Ā Ā Ā Ā Ā 

Origin of Southerm Asia Macaca species

55

7.62

5.13, 9.83

3.98

2.65, 5.89

2.65-9.83

Split P. cynomolgi-P. vivax

52

4.28

2.68, 6.09

2.30

1.22, 3.58

1.22-6.09

Origin of Catarrhini parasite (excluding P. ovale)

57

22.53

15.83, 28.79

14.76

9.86, 21.82

9.86-28.79

Split Papio-Macaca

56

12.41

8.83, 14.24

7.46

6.00, 10.71

6.00-14.24

Lorisiforms-Catarrhini parasite

58

25.48

17.90, 33.14

17.11

11.71, 24.94

11.71-33.14

Radiation Lorisiforms parasite

42

18.99

12.82, 25.63

13.60

9.20, 19.91

9.20-25.63

Radiation Apes parasite

35

13.92

8.86, 20.10

10.83

6.76, 16.36

6.76-20.10

Radiation Rodents parasite

38

15.12

9.58, 21.72

8.32

5.10, 12.60

5.10-22.71

Split P. falciparum-P. reichenowi

33

4.66

2.61, 7.54

3.77

2.21, 5.84

2.21-7.54

Origin of P. falciparum

31

0.42

0.04, 1.08

0.28

0.10-0.50

0.01-1.08

Origin of Plasmodium in mammals

60

37.78

26.24, 50.26

23.73

16.18, 35.02

16.18-50.26

Calibrations: node56, min = 6, max = 14.3; node57, min = 23.5; ABSMAX = 91

Ā Ā Ā Ā Ā Ā 

Origin of Southerm Asia Macaca species

55

8.28

6.50, 10.23

6.75

5.12, 8.42

5.12-10.23

Split P. cynomolgi-P. vivax

52

4.66

3.30, 6.29

3.93

2.50, 5.43

2.50-6.29

Origin of Catarrhini parasite (excluding P. ovale)

57

25.70

23.58, 30.09

26.27

23.5, 31.12

23.50-31.12

Split Papio-Macaca

56

13.41

11.58, 14.27

12.09

9.80, 14.30

9.80-14.30

Lorisiforms-Catarrhini parasite

58

28.91

25.17, 34.60

29.83

24.97, 35.72

24.97-35.72

Radiation Lorisiforms parasite

42

21.49

17.21, 26.88

23.59

18.93, 28.79

17.21-28.79

Radiation Apes parasite

35

15.78

11.29, 21.64

18.37

12.79, 24.03

11.29-24.03

Radiation Rodents parasite

38

17.20

12.46, 23.08

14.20

9.96, 18.89

9.96-23.08

Split P. falciparum-P. reichenowi

33

5.27

3.18, 8.23

6.39

4.27, 8.64

3.18-8.64

Origin of P. falciparum

31

0.48

0.04, 1.22

0.48

0.19, 0.81

0.04-1.22

Origin of Plasmodium in mammals

60

42.72

35.24, 53.03

40.97

32.89, 50.18

32.24-53.03

  1. Point time estimates and their associated 95% credibility intervals (CrIs) are shown in millions of years (Mya). Combined CrIs are also shown (cCrIs). Node numbers are listed in additional file 4. The absolute maximum for the ingroup root node (ABSMAX) was set at 91 Mya (see Methods for more details).