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Table 2 Major properties of proved type IIC enzymes.

From: Fused eco29kIR- and Mgenes coding for a fully functional hybrid polypeptide as a model of molecular evolution of restriction-modification systems

Enzyme

Other

subtypes

Recognition sequence

AdoMet influence

on REase

Type of MTase

Presence of separate M gene

AloI [16]

B, G, S

(7/12-13) GAACNNNNNNTCC

(12-13/7)

yes

m6A

no

BcgI [17]

B, G, H, S

(10/12) CGANNNNNNTGC (12/10)

yes

m6A

no

BseMII [18]

G, S

CTCAG (10/8)

yes

m6A

yes

BseRI [19]

G, S

GAGGAG (10/8)

yes

m6A

no

BsgI [20]

G, S

GTGCAG (16/14)

yes

m6A

no

BspLU11III

[21]

G, S

GGGAC (10/14)

yes

m6A

yes, two genes

CjeI [22]

B, G, S

(8/14) CCANNNNNNGT (15/9)

yes

m6A

no

RM.Eco29kI

This report

P

CCGC^GG

no

m5C

yes

Eco57I [23]

E, G, S

CTGAAG (16/14)

yes

m6A

yes

HaeIV [24]

B, G, P

(7/13) GAYNNNNNRTC (14/9)

yes

m6A

no

MmeI [25]

G, S

TCCRAC (20/18) or TCCRAC (21/19)

yes

m6A

no

PpiI [26]

B, G, S

(7/12) GAACNNNNNCTC (13/8)

yes

m6A

no

TstI [26]

B, G, S

(8/13) CACNNNNNNTCC (12/7)

yes

m6A

no