Figure 5
From: Biophysical and structural considerations for protein sequence evolution
dN/dS vs dS (proportional to simulation time) for surface (black), core (red) and binding site (green) residues is shown. Values reflect the mean of the most common allele in each population, with standard error bars indicating inter-population variation. Simulations using the informational scoring function in A), simulations using the physics-based scoring function in B).