Aeadsx gene
|
---|
Exon No.
|
Exon size(bp)
|
Splice-donor
|
Intron size(bp)
|
Splice-acceptor
|
N° of Y
|
---|
1?
|
---
|
---
|
---
|
---
| Â |
2
|
518
|    A G |
274879
|
N H
|
12
|
 |  |
TTGCAG/gtaggtgtgaggcata
| Â |
tctcctctcttttcag/GCAACC
| Â |
3a
|
45
|    P V |
43797
|
G P
|
10
|
 |  |
TACCAG/gtgagttcgctgttga
| Â |
tctcttctggtttcag/TTGGCC
| Â |
3b
|
48
|    T D |
85670
|
D E
|
9
|
 |  |
GAACAG/gtgcgtacttccttaa
| Â |
tcgtttccaatttcag/ACGACG
| Â |
4
|
135
|    E G |
13860
|
Q A
|
11
|
 |  |
ACGAAG/gtatgggggttcttac
| Â |
cttctctgcctcgcag/GTCAAG
| Â |
5a
|
461
|
n.c.
|
208
|
Q M
|
5
|
 |  |
gttgag/gtcattataagcttcc
| Â |
acataatgaccacagt/GCAAAT
| Â |
5b
|
465
|
n.c.
|
10392
|
Y D
|
8
|
 |  |
cgacag/gtactgctattggagg
| Â |
tcaatccctcaaacag/GATACG
| Â |
6
|
1063
|
n.c.
|
22437
|
n.c.
|
11
|
 |  |
acgaag/gtgagtgttctttttt
| Â |
ctcttttcttcaacag/tttcac
| Â |
7
|
449
|
n.c.
|
---
|
---
|
---
|
 |  |
tacacacgtacacattaaaatag
| Â | Â | Â |
Consensus
|    AG/gtRagt |  |
YYYYYYYYYYYYNYag/G
|
8,02 +/- 2,15
|
 |  |    C |  |  |  |
- The exon/intron/exon boundaries of Aeadsx gene are reported. Exonic coding sequences are shown in uppercase letters, and non-coding regions (n.c.) are in lowercase letters. Encoded aminoacids are reported above the first base of each triplet. R = A or G nucleotide. Y = T or C or nucleotide. N = any nucleotide. The number of pyrimidines (Y) in the 12 bp preceding the 3' splice-acceptor site (NYag) is indicated. The consensus number of pyrimidines (8.02) was derived from the analysis of 4688 Ae. aegypti splice-acceptor sites. The Aeadsx gene intron 5 (13,860 bp) represents the intron preceding the female-specific exon 5a, and its polypyrimidine stretch does not deviate significantly from the consensus. The splice-acceptor site of the short 208-bp intron preceding the female-specific exon 5b is a weak acceptor site, as is the female-specific exon 5b splice-donor site, which deviates significantly from the consensus sequence.