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Table 1 Difference of optimal codons depending on whether they end with -GC or -AT.

From: The surprising negative correlation of gene length and optimal codon use - disentangling translational selection from GC-biased gene conversion in yeast

Amino acid Gene length Expression Recombination
FOPAT: FOPfor aminoacids with AT-ending optimal codons
Ala
N = 53719 codons
+0.0229NS +0.2546*** Co:-0.0656**
nCo:-0.0217NS
spo11:-0.0856***
dmc1:-0.0540*
mre110:+0.0147NS
mre116:-0.0659**
Arg
N = 43139 codons
+0.0002NS +0.4301*** Co:+0.0293NS
nCo:+0.0265NS
spo11:+0.0297NS
dmc1:+0.0488NS
mre110:+0.0375NS
mre116:-0.0037NS
Cys
N = 13614 codons
+0.0535* +0.2293*** Co:-0.0162NS
nCo:-0.0239NS
spo11:-0.0229NS
dmc1:+0.0030NS
mre110:+0.0172NS
mre116:-0.0158NS
Gln
N = 38581 codons
+0.0603* +0.2076*** Co:-0.0777**
nCo:-0.0546*
spo11:-0.0495NS
dmc1:-0.0873***
mre110:-0.0532NS
mre116:-0.0565*
Glu
N = 65707 codons
+0.1396*** +0.1663*** Co:-0.0658**
nCo:-0.0573*
spo11:-0.0796**
dmc1:-0.1154***
mre110:-0.0252NS
mre116:-0.0822**
Gly
N = 49861 codons
+0.0470NS +0.4385*** Co:+0.0241S
nCo:+0.0230NS
spo11:+0.0298NS
dmc1:+0.0406NS
mre110:+0.0831**
mre116:-0.0037NS
Pro
N = 43069 codons
+0.0304NS +0.3114*** Co:-0.0509*
nCo:-0.0292NS
spo11:+0.0105NS
dmc1:-0.0481NS
mre110:+0.0116NS
mre116:-0.0348NS
Grouped
N = 307690 codons
R2 = 0.300***
P(GL)***,P(Expr)***,
P(dmc1)***P(mre110)**
+0.1271*** +0.3732*** Co:-0.0867**
mCo:-0.0556*
spo11:-0.0086***
dmc1:-0.1643***
mre110:-0.0601*
mre116:-0.1074***
F OP GC: FOP for aminoacids with GC-ending optimal codons
Leu
N = 96687 codons
-0.1031*** +0.3690*** Co:+0.1828***
nCo:+0.1451***
spo11:+0.2015***
dmc1:+0.2526***
mre110:+0.1206***
mre116:+0.1344***
Asn
N = 60930 codons
-0.1588*** +0.2880*** Co:+0.2101***
nCo:+0.2000***
spo11:+0.2687***
dmc1:+0.3655***
mre110:+0.1991***
mre116:+0.1866***
Asp
N = 60058 codons
-0.1995*** +0.1485*** Co:+0.1976***
nCo:+0.1500***
spo11:+0.2602***
dmc1:+0.3561***
mre110:+0.1437***
mre116:+0.1997***
Tyr
N = 32887 codons
-0.1850*** +0.2240*** Co:+0.1718***
nCo:+0.1401***
spo11:+0.2499***
dmc1:+0.3186***
mre110:+0.1834***
mre116:+0.1704***
Phe
N = 44129 codons
-0.1103*** +0.2729*** Co:+0.2689***
nCo:+0.1612***
spo11:+0.2628***
dmc1:+0.3413***
mre110:+0.1933***
mre116:+0.1772***
Lys
N = 72564 codons
-0.2207*** +0.3210*** Co:+0.2248***
nCo:+0.1475***
spo11:+0.2843***
dmc1:+0.3632***
mre110:+0.1471***
mre116:+0.2043***
His
N = 21966 codons
-0.1010*** +0.1060*** Co:+0.1193***
nCo:+0.1132***
spo11:+0.1623***
dmc1:+0.2096***
mre110:+0.1086***
mre116:+0.1357***
Grouped
N = 389221 codons R2 = 0.424,
P(GL)***,P(Expr)***
P(dmc1, mre110)***
-0.2604*** +0.4005*** Co:+0.2935***
nCo:+0.2291***
spo11:+0.3667***
dmc1:+0.5090***
mre110:+0.2341***
mre116:+0.2724***
  1. Spearman Rank Correlations between optimal codon use, gene length, expression, and various recombination measures for amino acids and groups of amino acids with either AT- or with GC-ending optimal codons. 1554 genes for which all amino acids were present at least four times were used. Presented for grouped variables are also MR results of variables whose log-transformation did not grossly deviate from a normal distribution. *P < 0.05, **P < 0.01,***P < 0.001, NS = not significant.