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Table 4 Controlling the effect of gene position.

From: The surprising negative correlation of gene length and optimal codon use - disentangling translational selection from GC-biased gene conversion in yeast

  Gene length Expression Recombination
F OP AT
N = 147193 codons
R2 = 0.260***
P(GL)NS,P(Expr)***,
P(dmc1, mre110)***
-0.0480NS +0.3696*** Co:-0.1064***
nCo:-0.0922***
spo11:-0.0442NS
dmc1:-0.1224***
mre110:-0.0520*
mre116:-0.0922***
F OP GC
N = 180789 codons
R2 = 0.445***
P(GL)NS, P(Expr)***,
P(mre110)*,
P(dmc1)***
-0.1289*** +0.3839*** Co:+3284***
nCo:+0.2472***
spo11:+0.3909***
dmc1:+0.4829***
mre110:+2648***
mre116:+0.2669***
F GC Opt
N = 70401 codons
R2 = 0.174***
P(GL)NS, P(Expr)NS P(dmc1,
mre110)***
-0.0751** +0.1216*** Co:+0.2735***
nCo:+0.1843***
spo11:+0.3232***
dmc1:+0.3837***
mre110:+0.2104***
mre116:+0.2368***
F GC Non-Opt
N = 126878 codons
R2 = 0.224***
P(GL)NS, P(Expr)***
P(dmc1,
mre110)***
-0.0481NS +0.0410NS Co:+0.2990***
nCo:+0.2339***
spo11:+0.3506***
dmc1:+0.4390***
mre110:+0.2311***
mre116:+0.2754***
  1. Spearman Rank Correlations between frequencies of optimal and GC-ending codons with gene length, expression, and various recombination measures after controlling for a potential effect of gene position. The same 1571 genes were used for all measures. Presented are also MR results of variables whose log-transformation did not grossly deviate from a normal distribution. *P < 0.05, **P < 0.01,***P < 0.001