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Table 2 Principal Component Analysis on Evolutionary Rate (ω) with (a) Gene Level Predictors, (b) Transcript Level Predictors, (c) Protein Level Predictors.

From: Evolutionary dynamics of human autoimmune disease genes and malfunctioned immunological genes

a. Gene Level Predictors
  Principal Component1 Principal Component2
Percent of the total variance
Correlation Coefficient (Spearman's ρ) with ω
27.502
-0.061**
21.912
0.113**
Major Contributing Factor in PCA1
Paralogs Number
Recombination Rate
0.789
0.805
---
---
Major Contributing Factor in PCA2
Single Nucleotide Polymorphism
Copy Number Variation
---
---
0.995
0.713
a. Transcript Level Predictors
Percent of the total variance
Correlation Coefficient (Spearman's ρ) with ω
39.071
-0.161**
 
Major Contributing Factor in PCA1
m-RNA abundance
Alternatively Spliced Exons
Disorderness
0.702
0
0.688
0.446
 
c.Protein Level Predictors
Percent of the total variance
Correlation Coefficient (Spearman's ρ) with ω
69.095
-0.321***
 
Major Contributing Factor in PCA1
Fraction of Phosphorylation Residues
Proportion of Buried Residues
0.557
0.743
 
  1. N.B.: * denotes P < 10-3; ** denotes P < 10-6; *** denotes P < 10-9.