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Table 2 Detection of positive selection of mammalian TLR5 using the branch-sites test

From: Adaptive evolution of Toll-like receptor 5 in domesticated mammals

Foreground branch(es)

LRT Foregroundd N /d S  = 1 versus foregroundd N /d S  > 1

d N /d S (branch)

Sites under positive selectiona

Artiodactyls

35.61 (p < 0.001)

4.76 (foreground)

L34*

S268**

I295*

I307*

I393*

Q495*

I621*

E630**

Cow

21.84 (p < 0.001)

140.91 ( foreground )

I393**

Q495*

H720*

Sheep

18.10 (p < 0.01)

493.28 ( foreground )

K326*

Pig

11.89 (p < 0.05)

29.07 (foreground )

E630**

  1. Results of branch-sites analysis of positive selection within mammalian TLR5. a posterior probabilities (Pb) of codons existing in d N /d S  > 1 site class * = Pb > 0.95 and ** Pb > 0.99.