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Figure 4 | BMC Evolutionary Biology

Figure 4

From: Evidence for a divergence in function between two glucocorticoid receptors from a basal teleost

Figure 4

Transactivation activity of the Pantodon buchholzi GR1 (PbGR1) and GR2b (PbGR2b). (A) Maximum fold induction with a variety of glucocorticoids and mineralocorticoids above the vehicle control (n = 3 + SEM) tested over a concentration range of 10-11 to 10-6 M, and dose- dependent stimulation of transactivation activity by 11-deoxycortisol (B), corticosterone (C) and cortisol (D). Values at each hormone concentration represent the average + SEM from at least 3 independent experiments, and are normalised to maximum activity for that hormone in each experiment.

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