Skip to main content

Table 2 Properties of Acipenser ruthenus (Ar) and Pantodon buchholzi (Pb) GRs in transactivation and binding assays with dexamethasone

From: Evidence for a divergence in function between two glucocorticoid receptors from a basal teleost

 

Transactivation EC50 (nM)

Maximum induction (−fold)

Binding Kd(nM)

Bmax(nmol/well)

ArGR

2.2 ± 0.7

277 ± 67

11.9 ± 3.2

0.3 ± 0.1

PbGR1

12.0 ± 1.3

469 ± 6

9.8 ± 1.4

1.2 ± 0.3

PbGR2b

1.5 ± 0.4

1079 ± 2

5.7 ± 0.7

1.17 ± 0.3

  1. Values represent the average and SEM of 3–5 independent experiments.