Genome-wide DNA methylation analyses in the brain reveal four differentially methylated regions between humans and non-human primates

Table 1 Information of samples

Sample ID	Species	Sex	Age (years)	Cortex Region
H1^a,d	Human	Male	40	PFC^c
H2^a	Human	Male	28	PFC^c
H3^a	Human	Male	59	PFC^c
H4^b	Human	Female	35	PFC^c
H5^b	Human	Male	7.5	PFC^c
M1^a,d	Rhesus macaque	Male	13	PFC^c
M2^a	Rhesus macaque	Male	9	PFC^c
M3^a	Rhesus macaque	Male	19	PFC^c
M4^b	Rhesus macaque	Male	16	PFC^c
M5^b	Rhesus macaque	Male	1-2	PFC^c
M6^b	Rhesus macaque	Male	11	PFC^c
M7^b	Rhesus macaque	Female	13	PFC^c
Chimpanzee1^d	Chimpanzee	Male	1.5	PFC^c
Chimpanzee2^d	Chimpanzee	Male	1.5	PFC^c
Rat1^d	Rat	Female	2 months	PFC^c
Rat2^d	Rat	Male	2 months	PFC^c

^athe 6 samples for MeDIP-Chip and MassARRAY analyses.
^badditional independent samples used for further validation.
^cprefrontal cortex.
^dthe samples used for multiple species comparison using bisulfite clone sequencing.

ISSN: 2730-7182