Table 3 Overrepresented Gene Ontology terms in human proteins containing particular LCR types
From: Dissecting the role of low-complexity regions in the evolution of vertebrate proteins
LCR | Gene Ontology term | Observed(%) | Total (%) | p-value |
|---|---|---|---|---|
A | cell cycle | 7 (10.77) | 691 (2.22) | 0,00062 |
A | regulation of transcription | 14 (21.54) | 2,208 (7.1) | 0,00016 |
G | RNA splicing | 5 (7.58) | 332 (1.1) | 0,00085 |
P | actin cytoskeleton organization | 9 (15.52) | 218 (0.83) | <0,00001 |
Q | regulation of transcription, DNA-dependent | 19 (38) | 3,841 (15.2) | 0,00007 |
ED | nucleosome assembly | 6 (16.67) | 360 (1.93) | 0,00006 |
SR | RNA splicing | 8 (61.54) | 329 (2.42) | <0,00001 |