The evolutionary and similarity whole-genome phylogenies of E. coli / Shigella . (A) The maximum parsimony tree was constructed using the concatenated LCBs that are shared by all of the 36 sequenced strains. The reliability of the topology was assessed by bootstrapping with 1000 pseudo-replicates. The phylogroup (A, B1, B2, D, E, F, S1, S3, SS or SD1) and pathotype (Commensal, InPEc, ExPEc, or Shigellosis) of each strain is indicated on the right. (B) The neighbor-joining phylogeny was constructed using the Jaccard distances. Only the LCBs that were absent in at least one strain and present in at least two strains were analyzed. The reliability of the topology was assessed by re-sampling the collinear regions 1000 times.