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Table 2 Results of Chi-square test for different datasets

From: The origins of the evolutionary signal used to predict protein-protein interactions

Dataset

Total pairs (POS | NEG)

Num pairs (+,+) (POS | NEG)

Num pairs (+,-) (POS | NEG)

Num pairs (−,-) (POS | NEG)

P-value

SP50L

40 | 91

5 | 4

9 | 16

26 | 71

0.161

SP50L-20p

39 | 91

8 | 3

5 | 17

26 | 71

0.005

UP50L

86 | 201

4 | 7

15 | 48

67 | 146

0.454

UP50L-20p

86 | 201

5 | 6

12 | 57

69 | 138

0.022

UP70L

63 | 106

6 | 6

15 | 27

42 | 73

0.636

UP70L-20p

63 | 106

4 | 9

14 | 32

45 | 65

0.412

UP70L-20p25s

62 | 105

4 | 9

22 | 31

36 | 65

0.685

UP70L-20p35s

64 | 107

5 | 9

16 | 30

43 | 68

0.888

  1. The table lists the number of pairs belonging to the 3 categories obtained after tree topology comparison (+,+) (+,-) (−,-) for the variants of the datasets: 20p – MSA with maximum of 20% gapped columns. 20p25s – MSA containing a maximum of 20% gapped columns and a maximum of 25 sequences, 20p35s – MSA containing a maximum of 20% gapped columns and a maximum of 35 sequences. Statistically significant p-values are highlighted in bold.