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Table 1 Step-down multiple testing corrected binomial probability support for strand-specific nucleotide mutation biases in MSV and TYLCV (Two-tailed probabilities in brackets)

From: Adaptive evolution by recombination is not associated with increased mutation rates in Maize streak virus

Mutation Recombinant data combineda VWMPCPLIRMat MSV:MatA MSV:VW MSV data combinedb MSV data combinedc TYLCVd
A → G : T → C 2 : 2 2 : 1 4 : 0 1 : 1 9 : 4 16 : 6 8 : 22
Binomial probability 0.750 (1.000) 1.000* (1.000*) 0.252 (0.500) 0.500 (1.000*) 0.174 (0.801) 0.054 (0.157) 0.020 (0.064)
A → C : T → G 2 : 0 1 : 1 3 : 1 0 : 5 6 : 6 11 : 10 10 : 12
Binomial probability 0.250 (1.000) 1.000 (1.000*) 0.500 (1.000*) 0.124 (0.252) 0.904 (1.000) 0.168 (1.000) 0.154 (0.832)
G → T : C → A 8 : 2 3 : 1 1 : 2 1 : 2 13 : 7 29 : 9 46 : 30
Binomial probability 0.132 (0.436) 1.000 (1.000*) 0.375 (1.000) 0.760 (1.000*) 0.222 (0.526) 0.004 (0.007) 0.051 (0.254)
G → A : C → T 4 : 11 1 : 3 3 : 6 5 : 6 13 : 26 18 : 30 48 : 55
Binomial probability 0.168 (0.354) 1.000 (1.000*) 0.492 (1.000*) 0.675 (1.000*) 0.060 (0.212) 0.052 (0.222) 0.124 (1.108)
  1. aRecombinant genomes obtained using the MatMPCPVW + VWMPCPMat and MatMPCPLIRVW + VWMPCPLIRMat parental chimaeric MSV genomes [47].
  2. bData combined using values from this study only.
  3. cData combined using values from this study and from van der Walt et al.[29].
  4. dData obtained from Martin et al. [48]*The calculated step-down multiple tested corrected p-values greater than 1 are simply represented as having a p-value of 1.