Figure 5

Selection analysis of PTP evolution (Clades 1 and 2). Unrooted phylogenetic trees were obtained from Bayesian inferences under the GTR + I + G substitution model. Posterior probabilities and bootstraps are indicated on the left of clade branches. Thick branches indicate ω>1 estimated under the branch-specific model in PAML. Some particular branches (indicated by arrows) or group of branches of a same clade with ω>1 have been tested by MA/MAnull model comparisons; among the branches tested stars indicate those under significant selection and NS those not significantly under positive selection (see Table 2). Although defined as different subclades PTP R and Δ have been analyzed together.