Table 1 Polyamine oxidase proteins sequences used in this study

[Spermine oxidase (SMO, EC number 1.5.3.16)]

Ailuropoda melanoleuca giant panda (Am)

predicted protein

[GenBank:EFB25976]

Anolis carolinensis green anole (An)

predicted protein

[ID:ENSACAP00000000096]

Bos taurus cattle (Bt)

protein

[Swiss-Prot:Q865R1]

Callithrix jacchus pygmy marmoset (Cj)

predicted protein

[ID:ENSCJAP00000039556]

Canis familiaris dog (Cf)

predicted protein

[GenBank:XP_860548]

Cavia porcellus guinea pig (Cp)

predicted protein

[ID:ENSCPOP00000015071]

Danio rerio zebrafish (Dr)

protein

[Swiss-Prot:Q6NYY8]

Dipodomys ordii kangaroo rat (Do)

predicted protein

[ID:ENSDORP00000002003]

Equus caballus horse (Eq)

predicted protein

[GenBank: XP_001495419]

Felis catus cat (Fc)

predicted protein

[ID:ENSFCAP00000002991]

Gallus gallus chicken (Gg)

predicted protein

[GenBank:XP_420872]

Gasterosteus aculeatus three-spined stickleback (Ga)

predicted protein

[ID:ENSGACP00000023283]

Gorilla gorilla gorilla (Go)

predicted protein

[ID:ENSGGOP00000018695]

Homo sapiens human (Hs)

protein

[Swiss-Prot:Q99K82]

Loxodonta africana elephant (La)

predicted protein

[ID:ENSLAFP00000010450]

Macaca fascicularis macaque monkey (Mf)

predicted protein

[GeneBank:BAE88223]

Macropus eugenii wallaby (Me)

predicted protein

[ID:ENSMEUP00000000797]

Microcebus murinus lemur mouse (Mu)

predicted protein

[ID:ENSMICP00000006250]

Monodelphis domestica grey short-tailed opossum (Md)

predicted protein

[GenBank:XP_001380279]

Mus musculus house mouse (Mm)

protein

[Swiss-Prot:NP_663508]

Myosotis lucifugus microbat (Ml)

predicted protein

[ID ENSMLUP00000014140]

Nomascus leucogenys gibbon (Nl)

predicted protein

[ID:ENSNLEG00000007689]

Ornithorhyncus anatinus platypus (Oa)

predicted protein

[GenBank:XP_001516006]

Oryctogalus cuniculus rabbit (Oc)

predicted protein

[ID:ENSOCUP00000006931]

Oryzias latipes medaka (Ol)

predicted protein

[ID:ENSORLP00000007986]

Pan troglodytes chimpanzee (Pt)

protein

[Swiss-Prot:XP_514493]

Pongo abelii sumatra orangutan (Pa)

predicted protein

[GenBank:XP_002830111]

Rattus norvegicus rat (Rn)

protein

[Swiss-Prot:XP_001079707]

Sus scrofa pig (Ss)

predicted protein

[GenBank:XR_04566]

Taeniopygia guttata zebra finch (Tg)

predicted protein

[GenBank:XP_002189301]

Takifugu rubripes japanese pufferfish (Tr)

predicted protein

[ID:ENSTRUP00000003466]

Tarsius syrinchtae tarsier (Ts)

predicted protein

[ID:ENSTSYP00000002870]

Tetraodon nigroviridis green spotted pufferfish (Tn)

predicted protein

[ID:ENSTNIP00000001941]

Tursiops truncatus dolphin (Tt)

predicted protein

[ID:ENSTTRP00000009415]

Xenopus laevis african clawed frog (Xl)

protein

[Swiss-Prot:Q6INQ4]

Xenopus tropicalis western clawed frog (Xt)

protein

[Swiss-Prot:Q28C17]

[Acetylpolyamine oxidase (APAO, EC number 1.5.3.11)]

Anolis carolinensis green anole (An)

predicted protein

[XP_003225445]

Bos taurus cattle (Bt)

protein

[Swiss-Prot:Q865R1]

Callithrix jacchus pygmy marmoset (Cj)

predicted protein

[ID:ENSCJAP00000009627]

Cavia porcellus guinea pig (Cp)

predicted protein

[ID:ENSCPOP00000010900]

Danio rerio zebrafish (Dr)

predicted protein

[GenBank:XP_690593]

Equus caballus horse (Eq)

predicted protein

[ID:ENSECAP00000000093]

Gallus gallus chicken (Gg)

predicted protein

[ID ENSGALP00000005619]

Gasterosteus aculeatus three-spined stickleback (Ga)

predicted protein

[GenBank: BT027282]

Gorilla gorilla gorilla (Go)

predicted protein

[ID:ENSGGOP00000004628]

Homo sapiens human (Hs)

protein

[Swiss-Prot:Q6QHF9-1]

Loxodonta africana elephant (La)

predicted protein

[ID:ENSLAFP00000007186]

Macaca mulatta macaque monkey (Ml)

predicted protein

[ID:ENSMMUP00000008331]

Macropus eugenii wallaby (Me)

predicted protein

[ID:ENSMEUP00000004459]

Monodelphis domestica short-tailed opossum(Md)

predicted protein

[ID:ENSMODP00000013113]

Mus musculus house mouse (Mm)

protein

[Swiss-Prot:Q4GX45]

Oryzias latipes medaka (Ol)

predicted protein

[ID:ENSORLP00000011447]

Pongo pygmaeus orangutan (Pp)

predicted protein

[ID:ENSPPYP00000003262]

Procavia capensis hyrax (Pc)

predicted protein

[ID:ENSPCAP00000005028]

Pteropus vampyrus megabat (Pv)

predicted protein

[ID:ENSPVAG00000002682]

Rattus norvegicus rat (Rn)

protein

[Swiss-Prot:Q7TPJ4]

Taeniopygia guttata zebra finch (Tg)

predicted protein

[GenBank:XP_002186801]

Takifugu rubripes japanese pufferfish (Tr)

predicted protein

[ID:ENSTRUP00000035024]

Tetraodon nigroviridis green spotted pufferfish 1 (Tn1)

predicted protein

[ID:ENSTNIP00000019636]

Tetraodon nigroviridis green spotted pufferfish 2 (Tn2)

predicted protein

[ID:ENSTNIP00000002385]

Tursiops truncatus dolphin (Tt)

predicted protein

[ID:ENSTTRP00000014996]

Xenopus laevis african clawed frog (Xl)

protein

[Swiss-Prot: Q5U4L6]

[Polyamine oxidases PAOs]

Anopheles gambia malaria mosquito (Ag)

predicted protein

[XP_312316.3]

Apis mellifera honey bee (Am)

predicted protein

[GenBank:XP_001122522]

Branchiostoma floridae amphioxus florida lancelet 1 (Bf1)

predicted protein

[GenBank:XP_002225568]

Branchiostoma floridae amphioxus florida lancelet 2 (Bf2)

predicted protein

[GenBank:XP_002606976]

Caenorhabditis elegans nematode roundworm (Ce)

predicted protein

[GenBank:NP_001023872]

Ciona intestinalis sea squirt (Ci)

predicted protein

[XP_002132119]

Drosophila melanogaster fruit fly (Dm)

protein

[Swiss-Prot:Q9VHN8]

Nasonia vitripennis jewel wasp (Nv)

predicted protein

[XP_001599761]

Nematostella vectensis starlet sea anemone (Ne)

predicted protein

[GenBank:XP_001626025]

Pediculus humanus corporis human body louse (Ph)

predicted protein

[GenBank:EEB13427]

Saccharomyces cerevisiae baker’s yeast (Sc)

protein

[GenBank:YDL174C]

Strongylocentrotus purpuratus purple urchin (Sp)

predicted protein

[GenBank:XP_001195328]

Tribolium castaneum red flour beetle (Tc)

predicted protein

[GenBank:XP_971067]

Trichoplax adhaerens tablet animal-Placozoa (Ta)

predicted protein

[GenBank:XP_002107802]