Figure 3

Schematic presentation of the NLR+GFP clone with wild type and mutated sequence in the pol gene. Shown are the HIV-1 reading frames. Black and gray rectangles represent the long terminal repeats (LTRs) and the out-of-frame env gene, respectively. GFP represents the GFP-expression cassette under the control of an internal CMV promoter. The mutated nucleotides are underlined. The indicated mutations do not change the amino acid sequence of the encoded protein.