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Figure 9 | BMC Evolutionary Biology

Figure 9

From: Endosymbiosis in trypanosomatids: the genomic cooperation between bacterium and host in the synthesis of essential amino acids is heavily influenced by multiple horizontal gene transfers

Figure 9

Overview of the biosynthetic pathways of essential amino acids in trypanosomatids. Dashed arrows: metabolite import; dotted arrows: reaction present in only some of the organisms analyzed; solid arrows: other reactions (a single arrow can summarize multiple steps); arrows surrounded by a gray box: enzymes possibly acquired through horizontal transfer from Bacteria to trypanosomatids (see main text). A. Contribution of symbiont-harboring trypanosomatids (SHT) and endosymbionts (TPE) based on the analysis of gene content in the genomes of A. deanei, A. desouzai, S. culicis, S. oncopelti, S. galati, and respective endosymbionts. B. Biochemical capability of trypanosomatids without symbionts (RT), based on the analysis of genomic data from H. muscarum, C. acanthocephali, and L. major.

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