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Figure 4 | BMC Evolutionary Biology

Figure 4

From: Contrasted evolutionary histories of two Toll-like receptors (Tlr4 and Tlr7) in wild rodents (MURINAE)

Figure 4

Mapping of evolutionary conservation of amino acid positions in a protein molecule based on the phylogenetic relations between homologous sequences. Conserved amino acid positions in LBR of TLR4 (a) and TLR7 (b). Structure of LBR was analysed in Consurf; computations were based on MrBayes phylogenetic trees and tertiary protein structures of R. norvegicus [Gen Bank Acc. KC811688/ KC811786]; most variable positions are highlighted in turquoise and numbered (grade 1); most conserved sites are in violet; yellow sites mark insufficient data; white sites have average conservation score; tables show residue variants at the phylogenetically variable positions with grade 1; codons with asterisk have been identified as those under positive selection by MEME.

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