Figure 1

The ANRIL gene and related potential transposons in vertebrates, mammals, and primates. The phylogenetic tree for the 27 organisms was adapted from the UCSC Genome Browser. The Infernal search was applied to the whole genome for five organisms whose genomes were not fully assembled (indicated by #) and to the chromosome containing CDKN2A/CDKN2B for the remaining organisms. Exons are indicated by square and rounded boxes (odd-numbered exons are labelled at the bottom). Transposons are indicated by asterisks in different colours (if a transposon occurs in > 500 Infernal hits in a chromosome, the asterisk has a black border). A square box with asterisk(s) above it indicates that the exon contains the transposon(s). A rounded box with asterisk(s) above it indicates that the exon does not contain the transposon(s), but the transposon(s) occur elsewhere in the chromosome. A square box without asterisks indicates that the exon does not contain transposons in all species. A rounded box without asterisks indicates that the exon does not contain the transposon(s), nor do the transposon(s) occur elsewhere in the chromosome. Asterisks without boxes indicate that the transposons were identified but the exons were not. The box length and shading indicate the length and score (reported by Infernal) of each exon. Distances between exons are not shown to scale.