A genetic polymorphism evolving in parallel in two cell compartments and in two clades

Table 2 Major PEPCK amino acid variation shared by Colias species

CEU, C. eurytheme; CME, C. meadii; n, variant counts; p, variant frequencies; aa, amino acids; x*, test parameter (normal deviate) for Goldstein’s exact binomial test for frequency difference [26]; P, probability of as much or more difference between samples by chance. Given n = 3 codons to test simultaneously, the corrected (Dunn-Sidak) minimum significance level α′ = [1 – (1– α)^1/n = 0.017 [27].

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