Table 1 Site model tests for positive selection

ASPM

14.015

11.390

0.001

0.001

0.007

5.351

0.020

3.504

0.005

0.005

CDK5RAP2

36.471

36.381

<0.001

<0.001

0.069

3.092

0.093

2.845

<0.001

<0.001

MCPH1

4.355

4.815

0.113

0.028

0.018

3.533

0.033

2.931

CENPJ

23.603

24.768

<0.001

<0.001

0.107

2.399

0.144

2.242

<0.001

<0.001

STIL

3.041

3.159

0.219

0.075

0.008

4.828

0.015

3.775

CEP152

9.359

9.303

0.009

0.002

0.113

1.815

0.194

1.576

0.036

0.008

WDR62

3.424

3.590

0.180

0.058

0.136

1.307

0.134

1.319

B) Non-primate mammals (n = 21)

Likelihood ratio

p-value

M2a

M8

Corrected p-value

Locus

M1a/M2a

M8/M8a

M1a/M2a

M8/M8a

prop >1

dN/dS >1

prop >1

dN/dS >1

M1a/M2a

M8/M8a

ASPM

48.679

59.244

<0.001

<0.001

0.011

2.802

0.036

1.798

<0.001

<0.001

CDK5RAP2

50.860

50.261

<0.001

<0.001

0.029

2.384

0.104

1.578

<0.001

<0.001

MCPH1

66.740

62.251

<0.001

<0.001

0.067

2.230

0.101

1.691

<0.001

<0.001

CENPJ

22.289

26.464

<0.001

<0.001

0.016

2.660

0.058

1.623

<0.001

<0.001

STIL

0.000

2.274

1.000

0.132

0.094

1.000

0.023

1.508

CEP152

48.651

39.601

<0.001

<0.001

0.020

2.447

0.098

1.467

<0.001

<0.001

WDR62

0.000

13.425

1.000

<0.001

0.228

1.000

0.010

2.148

<0.001

C) All mammals (n = 33)

Likelihood ratio

p-value

M2a

M8

Corrected p-value

Locus

M1a/M2a

M8/M8a

M1a/M2a

M8/M8a

prop >1

dN/dS >1

prop >1

dN/dS >1

M1a/M2a

M8/M8a

ASPM

87.071

86.279

0.000

0.000

0.015

2.662

0.046

1.705

0.000

0.000

CDK5RAP2

101.844

86.044

0.000

0.000

0.035

2.352

0.115

1.597

0.000

0.000

MCPH1

94.456

76.822

0.000

0.000

0.077

2.145

0.107

1.631

0.000

0.000

CENPJ

40.527

44.551

0.000

0.000

0.027

2.383

0.081

1.563

0.000

0.000

STIL

0.000

8.888

1.000

0.003

0.000

167.895

0.032

1.553

0.021

CEP152

97.383

70.324

0.000

0.000

0.022

2.604

0.062

1.698

0.000

0.000

WDR62

0.000

13.163

1.000

0.000

0.000

41.266

0.009

2.011

0.000