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Table 1 Statistical analysis on nucleotide substitution

From: Understanding the evolutionary structural variability and target specificity of tick salivary Kunitz peptides using next generation transcriptome data

    SNAP     Datamonkey   
   d N    d S      
Group Mean σ Variance Mean σ Variance *d N /d S *d N /d S **Evidence ***Selection type
1 0.56 0.02 0.006 1.01 0.18 0.03 0.56 0.69 No Negative
2 0.34 0.06 0.003 0.56 0.07 0.005 0.61 1.03 Yes Positive/negative
4 0.25 0.03 0.001 0.17 0.03 0.001 1.47 1.75 Yes Positive
5 0.31 0.21 0.045 0.88 0.37 0.14 0.35 0.62 No None
6 0.28 0.04 0.001 0.36 0.04 0.002 0.78 0.94 Yes Positive/negative
8 0.39 0.08 0.006 0.7 0.09 0.008 0.56 0.72 No Negative
9 0.17 0.03 0.001 0.34 0.05 0.002 0.5 0.51 No Negative
10 0.15 0.03 0.001 0.35 0.07 0.005 0.43 0.53 No None
  1. *The ratio between non-synonymous (d N ) and synonymous (d S ) nucleotide substitution per site analyzed by SNAP and by Datamonkey via SLAC [59].
  2. **Evidence for positive selection (p-value < 0.05) analyzed by Datamonkey via PARRIS [60].
  3. ***Evidence for selection type for specific sites (p-value < 0.05) analyzed via SLAC.