BMC Ecology and Evolution

Table 1 Statistical analysis on nucleotide substitution

From: Understanding the evolutionary structural variability and target specificity of tick salivary Kunitz peptides using next generation transcriptome data

			SNAP					Datamonkey
		d _N			d _S
Group	Mean	σ	Variance	Mean	σ	Variance	*d_N/d_S	*d_N/d_S	**Evidence	***Selection type
1	0.56	0.02	0.006	1.01	0.18	0.03	0.56	0.69	No	Negative
2	0.34	0.06	0.003	0.56	0.07	0.005	0.61	1.03	Yes	Positive/negative
4	0.25	0.03	0.001	0.17	0.03	0.001	1.47	1.75	Yes	Positive
5	0.31	0.21	0.045	0.88	0.37	0.14	0.35	0.62	No	None
6	0.28	0.04	0.001	0.36	0.04	0.002	0.78	0.94	Yes	Positive/negative
8	0.39	0.08	0.006	0.7	0.09	0.008	0.56	0.72	No	Negative
9	0.17	0.03	0.001	0.34	0.05	0.002	0.5	0.51	No	Negative
10	0.15	0.03	0.001	0.35	0.07	0.005	0.43	0.53	No	None

*The ratio between non-synonymous (d_N) and synonymous (d_S) nucleotide substitution per site analyzed by SNAP and by Datamonkey via SLAC [59].
**Evidence for positive selection (p-value < 0.05) analyzed by Datamonkey via PARRIS [60].
***Evidence for selection type for specific sites (p-value < 0.05) analyzed via SLAC.

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