Figure 3
From: Inactive alleles of cytochrome P450 2C19 may be positively selected in human evolution
Haplotype bifurcation plots and extended haplotype homozygosity diagrams for CYP2C19 slow metabolizing allele (* 2 ) in Europeans and Asians. A. CYP2C19 haplotype structure in Europeans. CYP2C19*2 containing AGT (haplotype 2) shows a branching pattern and the level of extended homozygosity is lower than observed in Yoruba. B. CYP2C19*2 haplotype structure in Japanese and Han Chinese. The CYP2C19*2-containing haplotype AGT (haplotype 2) has a branching structure and REHH values similar to those in Europeans.