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Table 1 F ST measure of population differentiation and minor allele frequencies at CYP2C19/9 locus in Gambians and in the three HapMap populations

From: Inactive alleles of cytochrome P450 2C19 may be positively selected in human evolution

 

FSTper locus

Allele frequency

CYP2C19

 

Gambians

Europeans

Asians

Yoruba

rs4244285 (CYP2C19*2)

0.016

0.23

0.15

0.27

0.15

rs12248560 (CYP2C19*17)

0.080

0.23

0.21

0.01

0.28

rs4986893 (CYP2C19*3)

0.295

0

0

0.53

0

rs7067866

0.078

0.39

0.57

0.61

0.29

rs4417205

0.011

0.18

0.15

0.27

0.18

rs4986894

0.015

0.18

0.16

0.27

0.14

CYP2C9

     

rs1799853 (CYP2C9*2)

0.05

0.03

0.09

0

0

Overall

0.098

    
  1. FSTAT 2.9.3 was used to estimate FST. The genotype data for the individual SNPs of the HapMap populations were retrieved from NCBI dbSNP BUILD 131.
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BMC Ecology and Evolution

ISSN: 2730-7182

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