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Figure 2 | BMC Evolutionary Biology

Figure 2

From: An evolutionarily biased distribution of miRNA sites toward regulatory genes with high promoter-driven intrinsic transcriptional noise

Figure 2

Genes with higher expression variability are targeted by more miRNAs. (A) Distribution of the coefficient of variation values for gene expression for 1st and 4th quartile groups. The coefficient of variation for each gene was calculated from meta-data set of gene expression profile across 886 arrays. (B) A scatter plot of the average gene expression variability versus the average number of distinct miRNA sites for vigintiles. Vigintiles were created by ranking genes based on the number of miRNA sites in their 3′ UTR. (C) A scatter plot of the average promoter GC content versus the average number of distinct miRNA sites for vigintiles. (D) A scatter plot of the average ratio of nucleosome favoring to disfavoring di-nucleotides versus the average number of distinct miRNA sites for vigintiles.

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