Table 1 Inferences from phylogenetic analysis of Runt domain sequences*
| Â | NEIGHBOR | PROML | PROTPARS | MRBAYES |
|---|---|---|---|---|
Monophyly of deuterostome homologues? | Yes (71 % bootstrap support for the deepest branch) | Yes | Yes for vertebrates and urochordates (74%), ambiguous for echinoderms | Yes (93 % posterior probability) |
Runx3 basal in vertebrates? | No | No | No | No |
Deepest deuterostome branch is a single-copy gene? | Yes | Yes | Yes | Yes |
Deepest protostome branch is a single-copy gene? | Unclear (unresolved topology of the nematode and spider paralogues) | Unclear (unresolved topology of the nematode and spider paralogues) | Unclear (unresolved topology of the nematode and spider paralogues) | Unclear (unresolved topology of the nematode and spider paralogues) |