Mutations of acetylcholinesterase which confer insecticide resistance in Drosophila melanogaster populations

Table 1 Point mutations in acetylcholinesterase involved in insecticide resistance.

Position in mature AChE of Torpedo californica	Mutation	Species	Reference
78	F77(115)S	Drosophila melanogaster	[8]
119	G(247)S	Culex pipiens	[18]
	S(228)G	Tetranychus urticae	[19]
128	D(237)E	Tetranychus urticae	[19]
129	I161(199)V	Drosophila melanogaster	[8]
	I(214)V	Bractocera oleae	[20]
150	V180L(260)	Musca domestica	[21, 22]
227	G265(303)A	Drosophila melanogaster	[8]
	G262(342)A	Musca domestica	[21, 22]
	G262(342)V	Musca domestica	[21, 22]
238	S(291)G	Leptinotarsa decemlineata	[23]
290	F330(368)Y	Drosophila melanogaster	[11]
	F327(407)Y	Musca domestica	[21, 22]
328	G365(445)A	Musca domestica	[20]
	G368(406)A	Drosophila melanogaster	This study
331	S(431)F	Myzus persicae (MpAChE2)	[24]
	F(445)W	Culex tritaeniorhynchus	[25]
	F(439)C	Tetranychus urticae	[19]
396	G(488)S	Bractocera oleae	[20]

Numbers in brackets refer to the precursor numbering. Corresponding position in Torpedo californica sequence has been added since this sequence is used as reference for the cholinesterase family.

ISSN: 2730-7182