Skip to main content
Figure 4 | BMC Evolutionary Biology

Figure 4

From: Structure and evolution of protein interaction networks: a statistical model for link dynamics and gene duplications

Figure 4

(a) The asymmetric link dynamics produces a broad connectivity distribution. The model prediction of the connectivity distribution of nodes with non-zero connectivity agrees well with yeast protein interaction data (filled diamonds). The solution of the rate equation (4) is shown as a solid line, the result of a computer simulation emulating the link dynamics encapsulated in (4) for a network of finite size is shown as circles (°). Nodes with the highest k (lower right) occur only once in the network. (b) High-connectivity vertices are preferentially connected to low-connectivity vertices, as also observed empirically. The figure shows the relative likelihood of the link distribution and the 'null distribution' of an uncorrelated random network, see text.

Back to article page