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Table 3 Comparison across species of the amino acid sequence conservation of Sin1 with some other conserved genes

From: The evolution of the Sin1 gene product, a little known protein implicated in stress responses and type I interferon signaling in vertebrates

 

Yeast

Drosophila

Frog

Chicken

Mouse

Cattle

Human

Histone H3

91.2%

98.5%

94.9%

95.6%

97.8%

98.5%

100%

β-actin

90.4%

97.9%

99.5%

100%

100%

98.1%

100%

CDK1

64.9%

71.7%

88.5%

93.3%

97.0%

98.7%

100%

Sin1

25.3%

31.9%

85.6%

90.0%

96.9%

99.0%

100%

  1. Values for percentage identities were obtained by aligning amino acid sequences from various species with their human counterparts. CDK, cyclin-dependent kinase. The GenBank accession numbers for sequences are as follows. Human (Homo sapiens): histone H3 (AAH66884), β-actin (NP_001092), CDK1 (P06493), Sin1 (NM_024117, BC002326). Cattle (Bos taurus): histone H3 (P16105), β-actin (AAM98378), CDK1 (P48734), Sin1 (BF230134, AV603930, CB433957, BM480500). Mouse (Mus musculus): histone H3 (NP_062342), β-actin (NP_031419), CDK1 (NP_031685), Sin1 (BQ713136, BF781677, BU152256). Chicken (Gallus gallus): histone H3 (I50245), β-actin (NP_990849), CDK1 (P13863); Sin1 (AF153127). Frog (Xenopus laevis): histone H3 (P02302), β-actin (AAC27796), CDK1 (P35567, Sin1 (BC043789). Fly (Drosophila melanogaster): histone H3 (NP_724345), β-actin (NP_511052), CDK1 (NP_476797), Sin1 (AE003814). Yeast (Schizosaccharomyces pombe): histone H3 (NP_595567), β-actin (NP_595618), CDK1 (NP_595629), Sin1 (NP_014563).